Naturally Yours Hyaluronic Acid Developer

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In "in vitro" human skin cultures, topical application of N-acetyl glucosamine and niacinamide stimulated hyaluronan synthesis. These treatments also led to an increase in collagen (procollagen-1) expression. Twice daily use of a facial moisturizer containing a combination of N-acetyl glucosamine and niacinamide for 4 to 8 weeks by women with moderate to severe fine and wrinkles reduced the appearance of facial fine lines and wrinkles, particularly in the eye area of the face. The in vitro hyaluronan results suggest that this effacement of fine lines and wrinkles is due at least in part to improved hydration of the skin. There are specific percentages in the actives used although this is considered proprietary information. References 1.Sayo T, Sakai S, Inoue S. Synergistic effect of N-acetylglucosamine and retinoids on hyaluronan production in human keratinocytes. Skin Pharmacol Physiol 2004; 17: 77-83. 2.Ghersetich I, Lotti T, Campanile G et al. Hyaluronic acid in cutaneous aging. Int J Dermatol 1994; 33: 119-22. 3.Weindl G, Schaller M, Schafer-Korting M, Korting HC. Hyaluronic acid in the treatment and prevention of skin diseases: molecular, biological, pharmaceutical and clinical aspects. Skin Pharmacol Physiol 2004; 17: 207-13. Method of Application Apply a pea-sized amount of this serum to your face and neck. Spritzing your face with spring water or a hydrosol will help this serum to glide across the skin gently yet effectively. Show more