Broad-spectrum backup for external and internal bacterial infections.External bacterial infections can spread fast, and many antibiotics either wreck your filter or stain the water.Seachem NeoPlex is a broad-spectrum neomycin antibiotic effective against most external infections of marine and freshwater fish. Used as directed, it won't discolor water or damage the biofilter, and it's well tolerated by invertebrates (delicate species may be stressed). Dose in water for external infections or in food for internal ones.NeoPlex is built on the science-driven chemistry Seachem has practiced since it was founded in 1979 in Madison, Georgia. As a company whose products are developed and manufactured in-house by chemists and backed by research, Seachem formulated NeoPlex so that, used as directed, it won't discolor the water or damage your biological filtration — and it's easily removed with activated carbon once treatment is complete. Remove sensitive invertebrates; turn off UV/ozone and remove carbon and Purigen. Dose 1 measure per 8 L (2 gallons) every 7 days, up to 3 weeks. Or mix with Focus into food for internal bacterial infections. Keep a broad-spectrum option on hand. Add to cart.Why Seachem NeoPlex Broad-spectrum neomycin: effective against most external bacterial infections of marine and freshwater fish, and against fungal infections too. Filter-safe and won't stain water: used as directed, it won't discolor the water or damage the beneficial bacteria in your biological filtration. Easily removed with carbon: lift residual medication with activated carbon (MatrixCarbon) before turning UV back on. Flexible Seachem chemistry: a research-backed neomycin sulfate formula that can be dosed in water for external infections or bound into food with Focus for internal ones. Best ForUse NeoPlex in freshwater or marine aquaria to treat external and internal bacterial infections; it is also effective against fungal infections. Dose in water for external infections, or bind it to food with Focus for internal ones. It is well tolerated by invertebrates when used as directed, though delicate species may be stressed — remove sensitive invertebrates before dosing in water.What It TreatsExternal and internal bacterial infections; also effective against fungal infections.DirectionsDosing in water: Remove all invertebrates. Turn off UV and ozone filters and remove chemical filtration (MatrixCarbon, Purigen). Use 1 measure (included) per every 8 L (2 US gallons). Repeat every 7 days to a maximum of 3 weeks. Treats external bacterial infections.Dosing in food (feed daily until clear, up to 1 week; treats internal infections): 1 scoop NeoPlex + 1 scoop Focus + 1 tbsp food (pellets or frozen) + a few drops of water if using dry food. Use with GarlicGuard to enhance palatability.After treating: Remove with activated carbon (MatrixCarbon) before turning UV back on.Active IngredientsNeomycin sulfate (43%). Inactive ingredients: excipients (57%).FAQIs NeoPlex safe for invertebrates? It is well tolerated by invertebrates when used as directed, but delicate species may be stressed — remove sensitive invertebrates before dosing in water.How do I remove NeoPlex after treatment? Run activated carbon (MatrixCarbon) in your filter after treating, and remove it before turning UV back on.Can I use NeoPlex in food? Yes. Mix 1 scoop NeoPlex + 1 scoop Focus + 1 tbsp food (with a few drops of water for dry food) and feed daily until clear, up to 1 week, to treat internal infections. GarlicGuard can improve palatability.