New Developments in Understanding Chronic Illnesses: The Role of Immune Dysfunction and Infections There are over 20 million Americans suffering from a group of chronic disabling disorders who are diagnosed without a clear elucidation of pathophysiologic mechanisms. Fibromyalgia, Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS), Neuropsychiatric illnesses, Posttreatment Lyme Syndrome, Pediatric Acute on Neuropsychiatric Syndrome (PANDAS/PANS). Target Audience Specialties – Allergy/Immunology, Family Medicine, Infectious Disease, Internal Medicine, Neurology, Pain Medicine, Pediatrics, Psychiatry, Psychology , Rheumatology Professions – Non-Physician, Nurse, Nurse Practitioner, Physician Overview There are over 20 million Americans suffering from a group of chronic disabling disorders who are diagnosed without a clear elucidation of pathophysiologic mechanisms. Fibromyalgia, Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS), Neuropsychiatric illnesses, Posttreatment Lyme Syndrome, Pediatric Acute on Neuropsychiatric Syndrome (PANDAS/PANS). Adding to this massive disease burden the CDC now estimates that of the 40% of Americans who were infected with COVID-19 1 in 5 continue to suffer with what is now referred to as Post-acute sequalae of COVID (PASC). Research has demonstrated that common to all of these conditions is dysregulation of the immune system resulting from an infectious insult. Dramatic advances have occurred in our understanding of all of these conditions as a result of COVID. We are entering an incredibly exciting period in medicine where these diseases are beginning to coalesce around an understanding of shared pathophysiology. We are entering a period of true hope for those millions who are suffering where we will finally be able to provide comprehensive solutions for their illness. This conference will bring together some of the leading researchers and clinicians from around the world to discuss the advances in our understanding of these conditions and breakthroughs in diagnostic and treatment options. Objectives After completing this activity, the participant will be able to: Summarize the role of the innate and adaptive immune system in chronic disease. Explain biological mechanisms of how infections incite immune dysfunction resulting in chronic disease. Describe new diagnostic testing and biomarkers for defining and identifying immune dysfunction in chronic illness. Identify clinical and case study examples using new and repositioned treatment modalities that have been shown to be effective in treating immune-mediated chronic disorders secondary to infection. Summarize long haul covid and it’s pathophysiology and new diagnostic and treatment modalities. Describe a new understanding of fibromyalgia as an immunologic disorder and the role of the immune system in Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome (ME/CFS). Recognize the role of infections and immune dysfunction as the cause of other neurologic, psychiatric, and behavioral disorders. Explain the role of gut microbiome in health and immune dysfunction. Identify the roles and responsibilities of members of the healthcare team involved in the collaborative care of patients with atypical immunological diseases. Integrate a team-based approach in the care of patients with atypical immunological diseases. Topics: NDUCI2023_brochureV2.pdf Session I Acute and Chronic Neurological Disorders in COVID-19 Potential Mechanisms of Disease.mp4 Session I NIH Data Myalgic Encephalomyelitis Chronic Fatigue Syndrome (ME CFS) Data.mp4 Session I Opening and Epidemiology How Big is the Problem Immune Dysregulation Secondary to Infections as a Cause of Chronic Disease.mp4 Session I The Enterovirus Theory of Disease Etiology in Myalgic Encephalomyelitis Chronic Fatigue Syndrome A Critical Review.mp4 Session II Introduction and Long Covid and Long Lyme Mental Health Implications.mp4 Session II Long Covid and Long Lyme Mental Health Implications.mp4 Session II Neuropsychiatric Diseases, Immune Dysfunction & Infections PANS PANDAS, POTS, PTLDS, Immune Dysfunction and Imaging & Testing for AEIE.mp4 Session II The Neuroimmunology of Social Stress Induced Sensitization.mp4 Session III Introduction and Chronic Pain and Infection Mechanisms, Causes, Conditions, Treatments, and Controversies.mp4 Session III The Autoimmune Aeitiology of Unexplained Chronic Pain.mp4 Session III The Brain and Gut Connection More Impactful Than You Think.mp4 Session IV Introduction and Current and Practical Techniques to Support the Gut Microbiome.mp4 Session IV Myalgic Encephalomyelitis Chronic Fatigue Syndrome (ME CFS).mp4 Session V Introduction and Diagnosis and Treatment of Chronic Inflammatory Conditions including Long COVID and ME-CFS.mp4 Session V Modulation of the Acquired Immune System Autoimmune Therapy Stem Cells Topic.mp4 Session VI Autoimmune Epilepsy Biomarker Study.mp4Session VI Introduction and Molecular Mimicry The Infection Connection to the Immune System and Chronic Disorders.mp4 Session VI The Axis of Infectious Immune as a Player in Neuro Immune Disease.mp4 Session VII Brain Changes and Clinical Outcome Correlates in Post-Treatment Lyme Disease.mp4 Session VII Introduction and The Clinical Significance of Metabolic Immune Interactions Implication for Treatment.mp4 Session VII Long Lyme Opportunities for Prevention and Treatment.mp4 Session VII Nutritional Supplements for Immune and Mitochondrial Dysfunction.mp4 Session VII What is Post-Treatment Lyme Disease Syndrome.mp4 Session VIII Denied Due to Lack of Medical Necessity Preventing & Responding to Insurance Denials for PANS PANDAS Treatments.mp4 Session VIII Introduction and Denied Due to Lack of Medical Necessity Preventing & Responding to Insurance Denials for PANS PANDAS Treatments.mp4 Session VIII Panel Post Treatment Lyme-PANS PANDAS.mp4 Session VIII Panel Treatment.mp4
