Alpha-lipoic acid is unusual among antioxidants in that it dissolves in both water and fat. Most antioxidants are one or the other — vitamin C works in watery environments, vitamin E in fatty ones. ALA moves through both, which is why it's sometimes described as a universal antioxidant. NFH provides 275 mg per capsule. Why there's biotin in it Each capsule also contains 50 mcg of biotin, and that's deliberate rather than filler. Alpha-lipoic acid and biotin are structurally similar enough that sustained higher-dose ALA can compete with biotin absorption. Including a small amount of biotin alongside it keeps that in balance — a detail many ALA products skip. How it behaves in the body ALA participates in the enzyme reactions mitochondria use to generate energy, and it has a recycling role with other antioxidants — vitamin C, vitamin E, glutathione and CoQ10 among them — helping return them to their active state. That regenerating effect is part of why it appears so often in antioxidant protocols rather than being taken alone. Note on how it's taken ALA is generally taken away from food, since some evidence suggests absorption is better on an empty stomach. Check your label and follow your practitioner's direction, as protocols vary. Format and exclusions 60 capsules at 275 mg. Free from gluten, dairy, soy, wheat, corn, sugar, artificial colours, artificial flavours and preservatives — a genuinely hypoallergenic formulation. Important before you start Speak to your doctor first if you take medication for blood sugar. Alpha-lipoic acid can affect glucose levels, and combining it with diabetes medication or insulin without supervision risks levels dropping too low. The same applies if you have thyroid disease or take thyroid medication. Also check with a healthcare professional if you are pregnant or breastfeeding, or scheduled for surgery. Discontinue if any adverse reaction occurs. Store cool and dry, away from direct sunlight, out of reach of children. About NFH Nutritional Fundamentals for Health is a Canadian practitioner-channel supplement brand.