Chronic inflammation is one of the most significant drivers of skin ageing, barrier dysfunction and skin condition persistence. Whether from rosacea, environmental stress, aggressive treatment products or the aftermath of aesthetic procedures, persistent low-grade neurogenic inflammation keeps the skin in a reactive state that prevents improvement and accelerates visible ageing. NOON DeFlame addresses this directly.An anti-inflammatory treatment combining clinically active calming actives with DermShield Technology to suppress the neurogenic inflammatory pathway that drives chronic skin reactivity. Formulated for patients with persistent redness, reactive skin conditions and post-procedure inflammation who need targeted anti-inflammatory treatment, not just soothing surface care.Who Is It For? Chronic redness and rosacea-prone skin with persistent inflammatory reactivity Post-procedure skin with significant redness, inflammation and reactivity Skin made chronically reactive by harsh previous skincare or over-treatment Those on GLP-1 medications experiencing increased skin reactivity during weight loss Those wanting an active anti-inflammatory treatment rather than a surface soothing product Patients in NOON programmes where inflammation management is a clinical priority How Does It Work?The anti-inflammatory active complex reduces the production and activity of pro-inflammatory cytokines and mediators at the skin level, actively reducing the inflammatory signalling that maintains chronic redness and reactivity. DermShield Technology simultaneously suppresses neurogenic inflammation at the skin surface, addressing the neurological component of inflammatory skin conditions alongside the cytokine pathway. Together they provide a more comprehensive anti-inflammatory approach than soothing botanical ingredients alone.Key Ingredients Anti-inflammatory active complex: Clinically active compounds that reduce pro-inflammatory cytokine production and signalling, actively calming inflammatory skin conditions rather than simply masking their surface symptoms. DermShield Technology (patented, NOON Aesthetics): Suppresses neurogenic inflammation at the skin surface to address the neurological pathway of inflammatory skin conditions alongside the cytokine-mediated pathway. Benefits Active reduction of chronic redness and inflammatory skin reactivity Addresses neurogenic and cytokine-mediated inflammation simultaneously Post-procedure inflammation calming beyond standard soothing products More comprehensive anti-inflammatory approach than botanical calming ingredients Suitable for rosacea-prone, post-procedure and chronically reactive skin What Results Can You Expect?Immediately: calmer, less reactive skin after the first application. At 2 weeks: measurably reduced baseline redness and reactivity with consistent daily use. At 6 weeks: significant reduction in inflammatory skin condition severity and improved tolerance of other treatment products.How We Use It at Face for SoulAs a pharmacist prescriber specialising in skin health, DeFlame is the targeted anti-inflammatory step I add to NOON programmes for patients whose chronic redness and reactivity is preventing progress from their other treatments. Before the inflammation is managed, active correction products cannot perform at their best. DeFlame addresses the inflammatory obstacle first.How to UseApply to cleansed skin morning and evening before moisturiser. Apply SPF 50 every morning. Pair with: NOON Smart Occlusive System or Optimal Moisturizing Guardian as the following moisturiser, and NOON HydroCalming Complex in the acute phase of post-procedure inflammation.Frequently Asked QuestionsIs it suitable for rosacea?Yes. DermShield Technology specifically targets neurogenic inflammation, a primary driver of rosacea reactivity. DeFlame is one of the most clinically appropriate anti-inflammatory steps for rosacea-prone skin in a programme context.Can I use it after a procedure?Yes. DeFlame is appropriate for post-procedure inflammation management. Always follow your clinician's specific post-treatment instructions on timing.Is it pregnancy safe?No retinoids or hydroquinone. Consult your midwife or obstetrician before starting new skincare during pregnancy.Is it vegan?Yes. NOON DeFlame is formulated without animal-derived ingredients.Is it cruelty-free?Yes. NOON Aesthetics does not test on animals.Clinical InsightAs a pharmacist prescriber specialising in skin health, DeFlame addresses the inflammation that prevents other treatments from working. For patients with chronic redness and reactivity, managing the inflammatory environment is the clinical priority before active correction can be effective.Complete Your RoutineMorning: NOON MicroSoft Cleanser, NOON Vitamin C Serum, NOON DeFlame, NOON Optimal Moisturizing Guardian, SPF 50. Evening: NOON cleanser, NOON DeFlame, NOON Smart Occlusive System.Why Buy From Face for Soul?At Face for Soul, DeFlame is in our protocol for patients with chronic inflammation because addressing the inflammatory environment clinically is what allows every other treatment to perform at its best. Contact us for guidance on how it fits into your programme.