Designs For Health NRF2 Modulator has been discontinued by the manufacturer. NRF2 Modulator was formulated to help promote the Nrf2 genetic pathway. The Nrf2 pathway is a mechanism of defense against oxidative stress (an imbalance between potentially damaging free radicals and antioxidants). This pathway regulates the production of important molecules that provide antioxidant activity, such as glutathione. It also regulates the production of detoxification enzymes to promote the metabolism and removal of hormones, toxins, medications, and other compounds. NRF2 Modulator supports the activation of this pathway to promote redox balance and a healthy inflammatory response. Supports antioxidant status in the body Promotes a healthy inflammatory response Ingredients Serving Size: 2 Vegetarian Capsules Amount/Serving Curcuminoid Powder (Curcumin C3 Complex®) 300 mg (Curcuma longa)(rhizomes)(containing three curcuminoids: curcumin, bisdemethoxycurcumin, demethoxycurcumin) [standardized to contain 95% curcuminoids] Red Grape Powder (Vinia®)(Vitis vinifera)(cells) 250 mg Quercetin 200 mg Olive Fruit Extract (Hytolive®)(Olea europaea)(fruit) [standardized to contain 10% hydroxytyrosol] 100 mg trans-Pterostilbene 100 mg Vitamin E Isomers (as DeltaGold® delta and gamma tocotrienols) 50 mg Other Ingredients: Cellulose, Quillaja extract, Vegetable stearate, Silicon dioxide Gluten Free. Soy Free. Non-GMO. Hytolive® is a registered trademark of Genosa I+D, S.A.Curcumin C3 Complex® and logo are registered trademarks of Sabinsa Corporation. Curcumin C3 Complex® is covered by U.S. Patent No. 5,861,415.DeltaGold® is a registered trademark of American River Nutrition, LLC and protected Suggested Use Take 2 capsules per day or as directed by your health-care practitioner. More Info. Nrf2 activates many genes and actions that are involved in scavenging free radicals and protecting the body from potential oxidative stress. When the body experiences excess free radicals, it activates Nrf2 and its associated antioxidant effects. Nrf2 is also involved in regulating the inflammatory response. Phytochemicals, such as those in NRF2 Modulator, can help activate the Nrf2 pathway to support the body’s own antioxidant defense network, support the body’s antioxidant status, and promote a healthy inflammatory response to support optimal health. 300 mg of Curcumin C3 Complex® featuring three highly bioactive forms of curcumin standardized to contain 95% curcuminoids 250 mg of Vinia® Red Grape Powder providing the whole matrix of red grape nutrients and polyphenols 100 mg of Hytolive® Olive Fruit Extract (standardized to contain 10% hydroxytyrosol), a solvent-free extraction of olive polyphenols from the by-product water of olive oil production 50 mg of vitamin E isomers as DeltaGold® delta- and gamma-tocotrienols to protect against lipid peroxidation.