NuMedica Methyl-Plex B Comprehensive Methylation support. A comprehensive formula designed to support healthy homocysteine levels and optimal methylation. The 5-MTHF in this formula Quatrefolic is the most biologically active form of folate. Allowing rapid uptake into the bloodstream. The 5-MTHF in this formula is also known as the ( L ) form of 5-MTHF since it is the reduced form of folate. B vitamins are provided in their active forms to support enhanced methylation and cardiovascular health. Recommended Use: Take 1 capsule per day or as directed by your healthcare practitioner. NuMedica Methyl-Plex B Facts: 1 capsule contains: Riboflavin (Vitamin B2) (as riboflavin-5'-phosphate) 25 mg Vitamin B6 (as pyridoxal-5'-phosphate) 25 mg Folate (as 600 mcg 6 (S)-methyltetrahydrofolic acid, glucosamine salt and 600 mcg 6(5)- methyltetrahydrofolate, calcium salt) 2,040 mcg DFE Vitamin B12 (as methylcobalamin) 1,000 mcg Trimethylglycine (as anhydrous betaine) 500 mg Other Ingredients: Hydroxypropyl methylcellulose (vegetable capsule), microcrystalline cellulose, magnesium stearate, silicon dioxide.