NutraMedix Japanese Knotweed is a concentrated liquid extract of Polygonum cuspidatum (Japanese Knotweed) — the highest natural source of Resveratrol, the polyphenol stilbene compound with extensive research on antioxidant, anti-inflammatory, neuroprotective, cardiovascular, and antimicrobial properties. Japanese Knotweed root contains up to 200x more Resveratrol than red wine per gram and also provides emodin and other stilbene compounds. 2oz liquid extract. NutraMedix is a Boca Raton, Florida-based nutraceutical company founded in 1998, sourcing botanical extracts under strict quality and sustainability standards directly from their native habitats in South America. Their herbal liquid extracts use a proprietary extraction process that preserves the full spectrum of active phytochemical constituents in a concentrated, bioavailable liquid form. Available at Beauty Riche — authorized NutraMedix retailer with same-day shipping.Resveratrol activates SIRT1 (a longevity-associated sirtuin enzyme), inhibits NF-κB inflammatory signaling, and acts as a potent antioxidant. Emodin (from the anthraquinone fraction of Japanese Knotweed) provides complementary antimicrobial activity — in vitro research has demonstrated emodin's activity against Borrelia burgdorferi and other spirochetal organisms. The combination of Resveratrol's immune modulation and emodin's antimicrobial activity makes Japanese Knotweed a dual-mechanism herb widely used in integrative Lyme and chronic infection protocols. The liquid format provides full-spectrum phytochemical delivery without the extraction limitations of standardized-only capsule forms.