You Must Be Aged Over 18 Years to Purchase This Product. Nytol is a sleep aid medication that is clinically proven to help relieve temporary difficulties getting to sleep. It works by blocking the normal actions of histamine, the chemical that stimulates arousal-promoting areas of the brain. This helps reduce alertness and promote that first drowsy stage of sleep, helping you to drift off into a restful, deeper sleep. Shown to help people fall asleep faster Can help obtain a longer and deeper sleep Suitable for temporary sleep difficulties due to stress, jet leg, personal problems Suitable for ages over 18 years For short term use only Pack size: 20 Tablets Instructions How to Use Adults, the elderly and children over 18 years; Take 1 single tablet 20 minutes before bedtime Do not take extra tablets if you wake up in the night Do not drive or operate machinery for 8 hours after taking Nytol Warnings Nytol One-A-Night 50mg Tablets are contraindicated in patients who are hypersensitive to the active substance (diphenhydramine hydrochloride) .Nytol One-A-Night 50mg Tablets are also contraindicated in patients with the following conditions:•Stenosing peptic ulcer•Pyloroduodenal obstruction•Phaeochromocytoma•Known acquired or congenital QT interval prolongation•Known risk factors for QT interval prolongation including a known cardiovasculardisease, significant electrolytes imbalance (hypokalaemia, hypomagnesaemia), family history of sudden cardiac death, significant bradycardia, concomitant use with drugs known to prolong the QT interval and/or induce Torsade de Pointes Side Effects Nytol One-A-Night 50mg Tablets should be used with caution in patients with myastheniagravis, epilepsy or seizure disorders, narrow-angle glaucoma, prostatic hypertrophy, urinaryretention, asthma, bronchitis and chronic obstructive pulmonary disease (COPD). Diphenhydramine has been associated with prolongation of the QT interval on theelectrocardiogram. During post-marketing surveillance there have been cases of QTinterval prolongation and torsade de pointes associated with overdose. Treatment should be stopped if signs or symptoms occur that may be associated withcardiac arrhythmia, and patients should seek immediate medical attention. Patientsshould be advised to promptly report any cardiac symptoms. Diphenhydramine should be used for the shortest possible duration. Tolerance and /or dependence may develop with continuous use. Do not take for more than 7consecutive nights without consulting a doctor. Seek medical advice if sleeplessness persists, as insomnia may be a symptom of serious underlying medical illness. In patients with moderate to severe hepatic impairment and moderate to severe renal impairment, a lower dose might be required. Should not be used in patients currently receiving monoamine oxidase inhibitors(MAOI) or those patients who have received treatment with MAOIs within the last two weeks. May increase the effects of alcohol, therefore alcohol should be avoided. Avoid use of other antihistamine-containing preparations, including topicalantihistamines and cough and cold medicines whilst taking Nytol One-A-Night50mg Tablets. Ingredients Each tablet contains 50mg Diphenhydramine Hydrochloride
