Aptamers are short, single-stranded DNA or RNA oligonucleotides that can bind specific targets — such as proteins, peptides, or small molecules — with high affinity and specificity. They function similarly to antibodies but offer higher stability, easy chemical modification, and reproducible synthesis. As an experienced oligo manufacturer, we provide high-quality, customizable aptamer oligos to support your discovery research, diagnostic assay development, and therapeutic innovation. Each aptamer can be provided in various quantities and delivery formats. Features Flexible Design: Custom DNA or RNA aptamers up to 180 nt (longer upon request). High Purity: DSL, PAGE and HPLC purification options available. Wide Range of Modifications: Biotin, fluorophores, amino, thiol, PEG, spacers, etc. Strict Quality Control: Verified by 100% MS and HPLC analysis; additional QC tests available upon request. Ready for SELEX or Target Validation: Synthesis suitable for screening or functional assays. Modification Options 5' modifications: Biotin, fluorophore (FAM, Cy5, TAMRA), amino, thiol, etc. 3' modifications: Spacer C3, inverted dT, quencher, biotin, etc. Internal modifications: dA*, dT*, fluorophore or quencher insertions. Backbone modifications: 2'-OMe, 2'-F, phosphorothioate linkage, etc. Not sure which modification suits your project? Our technical specialists can recommend the best design for your assay or SELEX round. Applications Target binding and screening (SELEX) Diagnostic assay development (ELISA, lateral flow, biosensors) Therapeutic research and drug delivery Biomarker detection and affinity purification Functional nucleic acid research