Estrogen is not a single hormone — it's metabolized into multiple downstream metabolites, some of which are protective and some of which are associated with increased breast, uterine, and prostate tissue proliferation when overproduced. EstroDIM by Ortho Molecular combines Indole-3-Carbinol (I3C) and 3,3'-Diindolylmethane (DIM) — the two key cruciferous vegetable metabolites that research shows work synergistically to promote a healthier ratio of estrogen metabolites, supporting hormonal balance for both women and men.Indole-3-Carbinol (I3C) is the parent compound found in broccoli, cauliflower, and Brussels sprouts. When consumed, it converts to DIM in the stomach — but also produces a range of additional beneficial metabolites including ICZ and NI3C that DIM alone doesn't provide. Formulating both I3C and DIM together (CDG EstroDIM formula) creates the complete spectrum of cruciferous indole metabolites that work together to support estrogen metabolism at multiple pathways simultaneously. The combined formula supports the conversion of estrogen toward the protective 2-hydroxyestrone pathway and away from the 16-alpha-hydroxyestrone pathway associated with proliferative effects.Relevant for: women experiencing PMS, perimenopause, or estrogen dominance symptoms; men concerned about elevated estrogen levels; individuals with a family history of hormone-sensitive conditions; those seeking to support healthy breast and prostate tissue. 30-capsule supply. Gluten-free, GMP certified. Take as directed by your healthcare professional. Available at Beauty Riche with same-day shipping.