B vitamins are essential cofactors in hundreds of biochemical reactions — from energy metabolism and DNA synthesis to neurotransmitter production, cardiovascular protection, and immune function. But most B-complex supplements use cheaper, synthetic forms that require conversion by enzymes that are genetically compromised in an estimated 40–60% of the population (MTHFR variants). Ortho Molecular Methyl B Complex delivers all eight essential B vitamins in their most bioavailable, biologically active methylated forms — bypassing MTHFR conversion bottlenecks entirely. The 120-capsule size provides a 4-month supply at the standard 1-capsule daily dose.Folate (as Quatrefolic® 5-MTHF) is the active, immediately usable methylated folate form that bypasses MTHFR — critical for DNA methylation, homocysteine clearance, and cardiovascular protection. Vitamin B12 (as Methylcobalamin) is the neurologically active form supporting nerve function, red blood cell formation, and the methylation cycle. Vitamin B6 (as Pyridoxal-5-Phosphate/P5P) is the active coenzyme form for neurotransmitter synthesis. Riboflavin-5'-Phosphate, Cocarboxylase, and Pantethine complete the active-form B vitamin backbone. Choline and Inositol provide synergistic methyl donor and cellular membrane support.120-capsule supply (4-month supply). Gluten-free, GMP certified. Ideal for MTHFR variants, homocysteine support, energy, mood, and neurological health. Available at Beauty Riche with same-day shipping.