Methylation is one of the body's most fundamental biochemical processes — occurring billions of times per second to regulate gene expression, neurotransmitter synthesis, cardiovascular protection via homocysteine clearance, DNA repair, and detoxification. When methylation is impaired — most commonly due to MTHFR gene variants, B vitamin deficiency, chronic stress, or aging — homocysteine accumulates in the blood, where it is a well-established independent risk factor for cardiovascular disease, cognitive decline, and neural tube defects.Methyl CpG is a physician-formulated methylation support formula delivering five key nutrients in their active, methylated forms that directly fuel the methylation cycle without requiring conversion. Folate (as Quatrefolic® 5-MTHF, 5-Methyltetrahydrofolate) is the active methyl-donor form of folate that bypasses MTHFR enzyme deficiency — directly donating methyl groups to the homocysteine remethylation pathway. Vitamin B12 (as Methylcobalamin) is the co-factor required for the methionine synthase reaction that converts homocysteine to methionine. Vitamin B6 (as Pyridoxal-5-Phosphate) supports the transsulfuration pathway — the alternative route for homocysteine removal that produces glutathione. Riboflavin-5'-Phosphate (active B2) is required for MTHFR enzyme activity. Zinc is a cofactor in the DNA methyltransferase enzymes.60-capsule supply. Essential for individuals with MTHFR variants, elevated homocysteine, cardiovascular risk, or neurological support goals. Gluten-free, GMP certified. Take 1 capsule daily or as directed. Available at Beauty Riche with same-day shipping.
