Specification Full name PCNA rabbit polyclonal antibody Alternative names 50 μl/100 μl Reactivity rabbit polyclonal Applications WB, IHC Host Rabbit Clone type rabbit polyclonal Target Background The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. (The background information is obtained from official databases and does not represent the product information.) Swissprot No P12004 Gene Accession BC000491 WB Predicted band size 29 kDa WB Positive control WB Recommended dilution 500-2000 IHC predicted cell location Predicted cell location: Nucleus IHC positive control Positive control: Human colorectal cancer IHC Recommed dilution Recommended dilution: 25-100 Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol WB PIC Description P100020-WB-1-P IHC PIC Description Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue using P100020(PCNA Antibody) at dilution 1/35
