Specification Full name PDGFRB rabbit polyclonal antibody Alternative names 50 μl/100 μl Reactivity rabbit polyclonal Applications WB, IHC Host Rabbit Clone type rabbit polyclonal Target Background The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. Swissprot No P09619 Gene Accession BC032224 WB Predicted band size 124 kDa WB Positive control WB Recommended dilution 1000-5000 IHC predicted cell location Predicted cell location: Cytoplasm IHC positive control Positive control: Human tonsil IHC Recommed dilution Recommended dilution: 50-300 Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol WB PIC Description P114437-WB-1-P IHC PIC Description Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or PDGFRB antigen-treated (Neutralization experiment) using P114437(PDGFRB Antibody) at dilution 1/90
