PEA Sooth Support Topical Cream 100ml

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You may receive either the old or new packaging. Our PEA Soothe Support Topical Cream provides an easy-to-use direct source of PEA (palmitoylethanolamide), a bio-identical acid ami de synthesized by healthy tissue in response to inflammation. As a non-psychoactive indirect endocannabinoid, PEA does not block pain signals like opioids or other analgesics. It works upstream by supporting glial and mast cells' healthy function, as supported by numerous studies. Glial cells are crucial to the nervous system and can exert inflammatory responses on neurons. Mast cells are immune system cells that respond to chemical signals from tissue injury. When mast cells degranulate, they release inflammatory cytokines, histamines, and other molecules, activating nociceptors (pain receptors). Inflammation Immune System Bone & Joint Health Directions: Apply to the skin on the affected area up to four times per day or as directed by a healthcare professional. For children, consult with a healthcare provider before use. Ingredients: Water, Simmondsia Chinensis Oil, Vitellaria Paradoxa Butter, Aloe Vera, Palmitoylethanolamide (PEA), Boswellia Serrata Resin, Commiphora Myrrha (Myrrh), Stearyl Alcohol, Stearic Acid, Polysorbate 60, Ascorbic Acid. Show more