PEG-MGF Description PEG-MGF (Pegylated Mechano Growth Factor) is a synthetic splice variant of IGF-1 studied for its role in muscle repair, protein synthesis, and cellular stress responses. Preclinical research indicates it promotes tissue regeneration, but it lacks human clinical trial data. Peptide Information Property Value Peptide Sequence Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys Molecular Formula C121H200N42O39 Molecular Weight 2867.2 g/mol CAS Number 108174-48-7 PubChem CID Synonyms Pegylated Mechano Growth Factor PEG-MGF Research Mechanism of Action & Preclinical Data Satellite Cell Activation: Studies show PEG-MGF activates satellite (stem) cells in skeletal muscle, which is critical for muscle fiber repair and hypertrophy. Protein Synthesis: It positively regulates protein synthesis pathways following mechanical stress or muscle damage. Extended Half-Life: The pegylation (attachment of polyethylene glycol) protects the peptide from rapid degradation, allowing for a longer half-life and broader distribution in animal models compared to native MGF. Tissue Repair: Beyond muscle, data from animal models (e.g., rabbits) suggests PEG-MGF may support bone repair by augmenting osteoblast (bone-forming cell) proliferation. Neurological Research: Preclinical rodent studies speculate that PEG-MGF can mitigate neuronal damage, reduce motor neuron loss, and improve cognitive performance in aging models. Safety Profile & Limitations Human Trials: There are no completed human clinical trials evaluating the safety or efficacy of PEG-MGF. Regulatory Status: As an experimental research compound, it is not approved for human use and is classified on the World Anti-Doping Agency (WADA) prohibited list. For Research Use OnlyThis compound is provided exclusively for in vitro laboratory research. It is not intended for human or animal consumption, diagnosis, treatment, or medical use. Not for dietary, cosmetic, or veterinary purposes. This product has not been evaluated by the U.S. Food and Drug Administration or any other regulatory authority. DisclaimerAll information is for educational purposes only. Humatide makes no claims regarding efficacy or safety. Purchasers are responsible for ensuring proper handling and use in compliance with all applicable laws and regulations. Terms of SaleBy purchasing from Humatide, you confirm that you are a qualified researcher with the knowledge and facilities to safely handle and store research chemicals. All sales are final. Humatide assumes no liability for misuse, misrepresentation, or unintended consequences arising from the use of this product.
