We love Perfect Prep for their variety of products they offer that help from calming, comforting and protecting different parts of our horses. Perfect Prep EQ™ Extreme Calming Paste is quick-acting, targeted equine calming support for increased focus during stressful situations. Suggested Use: For maximum effect use 80cc (one full oral syringe) 90 minutes prior to activity. Adjust for desired results. Effects begin 1 hour after administration and can last up to 6 hours. Feed carefully to assure swallowing. Flows best at room temperature. Use 90 minutes before increased stress. Effects begin within 1 hour and last up to 6 hours. Industry-leading full 80cc of targeted active ingredients. Works well alone or as part of the Perfect Prep EQ™ Calming System. Contains no prohibited substances. Active Ingredients: Proprietary blend of L-Tryptophan, Thiamin, Magnesium Amino Acid Chelate, Inositol.