Perque Activated B12 Guard delivers 2000mcg of Hydroxocobalamin B12 per lozenge in a sublingual format — providing maximum B12 absorption by bypassing the GI absorption pathway that is compromised in many individuals (particularly those with atrophic gastritis, intrinsic factor deficiency, vegans, and older adults). 100 lozenges.Hydroxocobalamin is the preferred form for several reasons: unlike Cyanocobalamin (which contains a cyanide molecule that must be removed), Hydroxocobalamin is a pure, naturally occurring cobalamin with superior cellular retention compared to Methylcobalamin. It converts readily to all active cobalamin forms the body needs (Methylcobalamin for methylation and Adenosylcobalamin for mitochondrial function). The sublingual lozenge format dissolves under the tongue, allowing B12 to be absorbed directly through the oral mucosa — bypassing the intrinsic factor-dependent GI absorption mechanism. Perque is a physician-grade clinical nutrition brand founded by integrative medicine pioneer Dr. Russell Jaffe, M.D., Ph.D., known for using only the highest-bioavailability nutrient forms (fully reduced, fully reacted) and rigorous quality standards. Available at Beauty Riche with same-day shipping.
