Specification Full name PGRMC2 rabbit polyclonal antibody Alternative names 50 μl/100 μl Reactivity rabbit polyclonal Applications WB, IHC Host Rabbit Clone type rabbit polyclonal Target Background PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas. Swissprot No O15173 Gene Accession BC016692 WB Predicted band size 24 kDa WB Positive control WB Recommended dilution 500-2000 IHC predicted cell location Predicted cell location: Cytoplasm IHC positive control Positive control: Human thyroid cancer IHC Recommed dilution Recommended dilution: 50-200 Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol WB PIC Description P105286-WB-1-P IHC PIC Description Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or PGRMC2 antigen-treated (Neutralization experiment) using P105286(PGRMC2 Antibody) at dilution 1/70
