High-Dose Corticosteroid Tablets for Immune and Inflammatory Conditions in Dogs Product Description Prednisone Tablets 50 mg is a prescription glucocorticoid corticosteroid used off-label in dogs to manage serious inflammatory conditions, autoimmune diseases, and certain cancers. At this higher strength, it is particularly suited to immunosuppressive therapy where a larger dose is required under close veterinary supervision. It works by binding glucocorticoid receptors to reduce inflammation and calm an overactive immune response throughout the body. Benefits Autoimmune Disease Treatment: Helps manage serious autoimmune conditions including lupus, immune-mediated hemolytic anemia, and pemphigus in dogs. Immunosuppressive Therapy: At higher doses, significantly suppresses the immune system in dogs requiring intensive treatment for immune-mediated disorders. Cancer Supportive Care: Used as part of chemotherapy protocols or palliative care plans for certain types of cancer in dogs. Emergency Inflammation Control: May be prescribed in emergency situations involving severe allergic reactions, anaphylaxis, or shock in dogs. Addison's Disease Management: Used to replace deficient corticosteroids in dogs with hypoadrenocorticism (Addison's disease) as part of an ongoing treatment plan. Ingredients Active Ingredients Prednisone 50 mg per tablet How to Use Prednisone is a prescription-only medication. A valid veterinarian prescription is required to purchase this product. Please follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet. Disclaimer: Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet. Many dogs take tablets more willingly when they are hidden inside a flavoured pill pocket or soft treat wrap. It is a simple and stress-free way to ensure your dog receives their full dose without any fuss. Shop Pill Pockets for Dogs Additional Information Precautions Not for Cats: Cats cannot efficiently convert prednisone to its active form; prednisolone should be prescribed for cats instead. Avoid in Fungal Infections: Do not use in pets with a systemic fungal infection unless specifically directed by a vet for Addison's management. Liver Dysfunction Caution: Pets with poor liver function may not convert prednisone effectively; prednisolone may be prescribed instead in these cases. Never Stop Abruptly: Prednisone must always be tapered gradually under veterinary guidance; sudden discontinuation can cause serious health complications. Avoid with NSAIDs: Concurrent use with non-steroidal anti-inflammatory drugs significantly raises the risk of gastrointestinal ulcers and internal bleeding. Caution in Diabetic Pets: Prednisone can elevate blood sugar levels and worsen diabetes; close monitoring and dose adjustment may be required. Not for Young Animals: Use with caution in puppies as long-term corticosteroid use can inhibit normal growth and development. Possible Side Effects Increased Thirst and Urination: Polydipsia and polyuria are among the most frequently reported effects in dogs on corticosteroid therapy. Increased Appetite: Many dogs experience a noticeably heightened appetite, which can lead to weight gain over time if unmanaged. Gastrointestinal Ulcers: Signs include loss of appetite, black or bloody stools, and bloody vomiting; stop the medication and contact your vet immediately. Behavioural Changes: Restlessness, aggression, or mild personality shifts can occur, particularly at higher doses or with prolonged use. Cushing's Disease Risk: Long-term use at higher doses can lead to signs of iatrogenic Cushing's disease including pot belly, muscle wasting, and hair coat changes. Increased Infection Risk: As an immune suppressant, prednisone reduces the body's ability to fight infection; monitor your dog closely for any signs of illness. Storage Information Room Temperature Storage: Store tablets at between 59°F and 86°F (15°C to 30°C), away from direct sunlight and heat sources. Protect from Moisture: Keep in a tightly sealed container to prevent humidity and moisture from degrading the tablets. Keep Out of Reach: Store securely away from pets and children to prevent accidental ingestion of this high-dose corticosteroid. NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial. Shipping & Return We offer ground, express, and priority delivery; see our shipping policy for details. For return instructions or product concerns, please refer to our detailed refund policy. Prescription items are NON-RETURNABLE and NON-REFUNDABLE. Frequently Asked Questions Q1: Why is prednisone 50 mg prescribed for dogs rather than a lower strength? Ans: The 50 mg strength is typically prescribed when a dog requires an immunosuppressive dose for serious conditions such as autoimmune disease or cancer. At these higher doses, the medication more significantly suppresses the immune system. Your veterinarian will determine the appropriate dose based on your dog's weight and diagnosis. Q2: Can prednisone cause Cushing's disease in dogs? Ans: Yes, prolonged use of prednisone at higher doses can lead to a condition known as iatrogenic Cushing's disease in dogs. Signs include a pot belly, muscle wasting, hair coat changes, and excessive thirst. Your veterinarian will monitor your dog closely and aim to use the lowest effective dose for the shortest time possible. Q3: What monitoring is recommended for dogs on long-term prednisone therapy? Ans: Veterinarians typically recommend regular bloodwork including a complete blood count and chemistry panel, urinalysis, and blood pressure monitoring for dogs on ongoing prednisone treatment. Blood sugar levels and ACTH stimulation tests may also be used depending on the dose and duration of use. Q4: Is it safe to give prednisone to a dog with diabetes? Ans: Prednisone must be used with extreme caution in diabetic dogs as it can raise blood glucose levels and significantly destabilise diabetes management. If your dog has diabetes, inform your veterinarian before starting this medication, as dose adjustments or closer glucose monitoring may be required. Q5: What should I do if I accidentally miss a dose of prednisone for my dog? Ans: If a dose is missed, give it as soon as you remember and then continue with the regular schedule. If it is almost time for the next dose, skip the missed one and resume normally. Never give two doses at once, and never stop this medication suddenly without speaking to your veterinarian first.
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