Spermidine Supplement · Capsules · Two Variants Primeadine® by Oxford Healthspan A capsule supplement standardised to spermidine — a polyamine compound naturally present in many foods. Available in two formulations: Original (concentrated wheat germ extract) and Gluten-Free (whole-food blend). Original: 90 capsules per bottle · 1 mg standardised spermidine per 3-capsule serve.Gluten-Free: 1.2 mg plant-derived spermidine per 2-capsule serve. About Spermidine Spermidine is a polyamine — a small organic compound made up of carbon, hydrogen, and nitrogen. It’s naturally present in many foods, including: Wheat germ (one of the richest natural sources) Aged cheeses (particularly blue cheese) Mushrooms Soybeans and dried soy products Legumes (including green peas) Some shellfish Various meats Spermidine is also produced naturally by the body and by certain bacteria in the gut. The combination of dietary intake and internal production contributes to the body’s overall polyamine content. Two Formulations Available Primeadine Original A capsule supplement made from concentrated wheat germ extract. The extract is defatted (to prevent the natural oils in wheat germ from going rancid) and standardised to provide 1 mg of spermidine per 3-capsule serving. Ingredients: Concentrated wheat germ extract (contains wheat — gluten) Maltodextrin (acts as a prebiotic fibre / resistant starch) Hypromellose capsule (plant cellulose, vegan) 90 capsules per bottle (30 servings at 3 capsules per serve). Primeadine GF (Gluten-Free) A capsule supplement made from a whole-food blend sourced and manufactured in Okinawa, Japan. Provides 1.2 mg of plant-derived spermidine per 2-capsule serving. Ingredients: Chlorella Shikuwasa (Citrus depressa) skin Turmeric root Hypromellose capsule (plant cellulose, vegan) In addition to spermidine, the whole-food blend naturally contains trace amounts of putrescine (another polyamine), as well as naturally-occurring small amounts of vitamin D2, vitamin K, folate, vitamin B12, biotin, pantothenic acid, iron, and lutein. Suitable for vegans and vegetarians. Gluten-free and soy-free. Product Specifications Format Vegetable cellulose (hypromellose) capsules Original — Capsules per Bottle 90 (30 servings at 3 capsules) Original — Spermidine 1 mg standardised per serve (from concentrated wheat germ extract) GF — Spermidine 1.2 mg plant-derived per 2-capsule serve Batch Testing Every batch tested for spermidine content Made In Original: USA / Europe · GF: Okinawa, Japan Storage Store in a cool, dry place. Keep tightly closed after opening. Directions for Use Primeadine Original: Build up gradually over three days. Take 1 capsule with liquid at mealtime on Day 1, 2 capsules on Day 2, and 3 capsules on Day 3. If you experience any digestive discomfort, reduce the dose by 1 capsule and rebuild gradually. Primeadine GF: Take 2 capsules daily, preferably before 2pm. Capsules can also be opened and the contents mixed into a cold or room-temperature drink or smoothie. Refer to the bottle label for full directions. Do not exceed the recommended daily intake. ⚠ Allergen Notice Primeadine Original contains wheat (gluten). Not suitable for individuals with a wheat allergy or gluten intolerance. If you are sensitive to gluten or wheat, the gluten-free version (Primeadine GF) is available as an alternative. Good to Know What is a polyamine? Polyamines are small organic compounds made up of carbon, hydrogen, and nitrogen, with multiple amine groups (functional groups containing nitrogen). They’re present in all living cells and naturally occur in many foods. Why is the wheat germ extract defatted? Wheat germ contains natural oils that can go rancid over time. By removing the oil component (defatting), the extract has better shelf stability and avoids the off-flavours that develop in oxidised wheat germ. What is the role of maltodextrin? The Original formula includes a specific type of maltodextrin that functions as a prebiotic fibre and resistant starch — meaning it isn’t digested in the small intestine, but passes to the large intestine where it can be fermented by gut bacteria. Why does Primeadine GF use Okinawan ingredients? The Gluten-Free formula sources its whole-food ingredients (chlorella, Shikuwasa citrus skin, turmeric) from Okinawa, Japan. Shikuwasa (Citrus depressa) is a small green citrus fruit native to Okinawa and Taiwan, traditionally used in Okinawan cuisine. Why the build-up dosing approach? For the Original wheat germ extract, building up the dose over three days helps the digestive system adjust to the supplemental fibre content (from the maltodextrin component). This is the same principle as gradually introducing any fibre supplement. Important Information Primeadine Original contains wheat (gluten). Not suitable for individuals with wheat allergy or gluten intolerance. Always read the label and follow the directions for use. Do not exceed the recommended daily intake. Use only if the seal is intact. Keep out of reach of children. Consult a qualified healthcare practitioner before use if you take prescription medication, are recovering from surgery, are pregnant or breastfeeding, or have any pre-existing medical condition. Discontinue use and consult a practitioner if any adverse reaction occurs. Adult use only. Not recommended for children. This product is not intended to diagnose, treat, cure or prevent any disease.
