Provita Ptero Gene™ SIRT1 CRF Anti-aging antioxidants - Provides unique antioxidants. There are many species of antioxidants, but not all are created equal. Although Pterostilbene is a phenol that is chemically related to Resveratrol, it differs by increased bioavailability and by well-defined activity in the body. Pterostilbene is isolated from the stem heartwood of Pterocarpus marsupium while resveratrol is extracted from the root of Reynoutria japonica (synonyms Fallopia japonica and Polygonum cuspidatum). Although they are both antioxidants, resveratrol and pterostilbene complement each other by the outcomes of their specific antioxidant effects. The antioxidant effect of resveratrol allows for the activation of calorie restriction mimetics and telomere maintenance factors, with the primary outcomes being cardiovascular and anti-aging effects. Pterostilbene acts as an antioxidant by activating AMPK (AMP-activated protein kinase) that regulates energy metabolism, and by activating Sirtuin 1. Obesity and aging diminish Sirtuin 1. Sirtuin 1 is NAD dependent, therefore increasing NAD+ levels can enhance the effect of pterostilbene. SIRT1 is one of the most important transcriptional factors that drives many cellular activities, like energy metabolism, cell survival, DNA stability, inflammation, and circadian rhythms. The added Quercetin is itself an antioxidant complementing Resveratrol and Pterostilbene. At the same time when Quercetin and Medium Chain Triglycerides (MCT) are associated with Resveratrol and Pterostilbene, the overall bioavailability of these antioxidants can be potentiated. Added specialized Piperine extract – Bioperine® (Sabinsa Corp.) – helps to increase resveratrol delivery. Benefits Provides unique antioxidants Increases antioxidant bioavailability Protects against oxidative stress Activates Calorie Restriction Factor (CRF) Ingredients Serving Size: 2 Veggie Capsules Amount/Serving Medium Chain Triglycerides (MCT) 200 mg Pterostilbene (Pterocarpus marsupium) 100 mg Trans Resveratrol Complex Japanese Knotweed Extract (Reynoutria japonica) (Rhizome) 100 mg Quercetin Phytosome(Sophora japonica extract) (flower) 39 mg BioPerine® Black Pepper Extract(Piperum nigrum) (fruit) standardized to contain 95% Piperine 14 mg Other Ingredients: Microcrystalline cellulose, hypromellose (vegetarian capsule), ascorbyl palmitate. Non-GMO. Gluten Free. Soy Free. Dairy Free. Vegan This product is manufactured and packaged in a facility which may also process milk. soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish. BioPerine® is a registered trademark of Sabinsa Corp., USA Suggested Use Two capsules daily preferably prior to a meal as a dietary supplement, or as directed by a healthcare professional. WARNING: Consult a health care practitioner prior to use if you are pregnant or breastfeeding or if you are taking any other medications or natural health products, as resveratrol and piperine may alter their effectiveness, or if symptoms worsen or if they persist for more than 2 weeks. Some people may experience an increase in appetite. Do not use if seal is broken. Keep out of reach of children. Keep sealed, store in a cool, dry place at 15–25ºC.
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