PURE OMEGA HPWHAT IT DOESPROVIDES ESSENTIAL OMEGA-3 FATTY ACIDSPure Omega products provide a triglyceride form of omega-3 fatty acids sustainably sourced from anchovies, sardines, herring, tuna, and mackerel.Every lot of Pure Omega is tested for purity and labeled potency claims. The results of these tests are available to you using the lot number found on each bottle. Check your product purity here.HOW IT WORKSEPA & DHA HELP SUPPORT ESSENTIAL FUNCTIONS*Omega-3 essential polyunsaturated fatty acids have distinct chemical structures and physiologic functions that distinguish them from other families of essential fatty acids. Often lacking in Western diets, omega-3 fatty acids compete with other fatty acids in the body for cyclooxygenase (COX) and lipoxygenase (LOX) enzyme metabolism, incorporation into cell membranes, and the synthesis of lipid mediators.1-3 The long-chain omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are almost exclusively marine-derived and act together to influence membrane fluidity and signal transduction pathways.4EPA and DHA are abundantly enriched in the retina, brain, and heart tissues.5-7 Each have preferential distribution within the phospholipid bilayer of cell membranes and have been shown to exert unique biological actions.4Humans have limited capacity to endogenously produce EPA and DHA; therefore they are considered essential fatty acids. Dietary supplementation of EPA and DHA is an effective way to increase intake of these essential fatty acids.REFERENCESSimopoulos AP. J Am Coll Nutr. 2002;21(6):495-505.Surette ME. CMAJ. 2008;178(2):177-180.Calder PC. Br J Clin Pharmacol. 2013;75(3):645-662.Mason RP. Curr Atheroscler Rep. 2019;21:2.Jeffrey BG et al. Lipids. 2001;36(9):859-71.Kim HY et al. Prog Lipid Res. 2015;0:1-18.Jump DB et al. J Lipid Res. 2012;53(12):2525-45.
