Advanced support for hormonal balance, skin health, and overall well-being in women Benefits Supports healthy estrogen levels with bioidentical estradiol Promotes skin hydration, elasticity, and a more youthful appearance Aids in maintaining bone density and skeletal strength Supports cardiovascular function already within normal range Encourages mood balance, mental clarity, and emotional well-being Helps maintain vaginal and urogenital tissue health and comfort Provides targeted support during perimenopause and menopause How It WorksEstradiol (E2) is the most potent and biologically active form of estrogen in the body, playing a central role in regulating reproductive health, bone density, cardiovascular function, brain health, and skin integrity. As natural estradiol levels decline with age, particularly during perimenopause and menopause, the body may experience changes in these systems. Estradiol+ is a topical bioidentical hormone serum designed to deliver estradiol through a nanoemulsified system for enhanced absorption through the skin. This method supports efficient uptake and consistent delivery of estradiol to tissues throughout the body. By replenishing estradiol, this formula helps support estrogen receptor activity, which is essential for maintaining structural integrity, metabolic balance, and overall physiological function. The inclusion of skin-supportive compounds further enhances the formula by promoting hydration, soothing effects, and skin vitality. Key Ingredients Estradiol (E2) – The primary and most potent form of estrogen, supporting bone health, cardiovascular function, cognitive performance, and hormonal balance. Nanoemulsified Delivery System – Enhances transdermal absorption and bioavailability for efficient systemic delivery. L-Theanine – Supports relaxation, stress balance, and mental clarity. EGCG (Epigallocatechin Gallate) – A potent antioxidant that supports cellular protection and skin health. Hyaluronic Acid – Helps maintain skin hydration, elasticity, and moisture retention. Luteolin Extract – A plant-derived flavonoid that provides antioxidant and calming support for skin and cellular health. Professional FormulationFormulated under professional guidance, Estradiol+ combines bioidentical estradiol with a nanoemulsified delivery system and supportive botanical compounds to enhance both hormonal delivery and skin health. This topical serum is designed to support systemic estrogen balance while also promoting skin vitality, hydration, and overall well-being. Suggested Pairings Works well with NAD+ IV therapy to support cellular energy, repair, and overall vitality Complements BHRT protocols as part of a comprehensive hormone optimization program Often used alongside progesterone or Bi-Est formulations for balanced estrogen support Ideal for individuals seeking support for perimenopause, menopause, or estrogen-related symptoms Always check with your doctor before using a new product or supplement if you have any questions or concerns about how a product may affect your current health, medications, pregnancy, or breastfeeding. All sales are final and cannot be returned or exchanged.