Ortho Molecular Reacted Iron Women's Health Reacted Iron provides 29 mg of elemental iron in the form of ferrous bisglycinate, an amino acid chelated iron designed for enhanced absorption, optimal utilization, and gastrointestinal (GI) tolerance. Iron, an essential mineral, plays a pivotal role in maintaining optimal health. Adequate iron levels are essential for numerous physiological functions, including oxygen transportation, energy production, cognitive function, cell division, biotransformation, and immune cell support. Supplementing with a bioavailable and well-tolerated form of iron is paramount to maintaining healthy levels and long-term adherence. Low-bioavailability iron supplements are associated with GI side effects like abdominal cramping, nausea, constipation, or diarrhea in up to 80% of individuals, resulting in a 50% early discontinuation rate. Unlike many conventional iron supplements, ferrous bisglycinate is associated with fewer GI side effects, including gas, bloating, and constipation. Key Benefits and Features: Provides Safe, Highly Absorbed Iron for a Variety of Protocols High-Concentration Iron for Energy Support Supports Oxygen Transport and Energy Production Ingredients Serving Size: 1 Capsule Amount/Serving Iron (as Ferrochel Ferrous Bisglycinate Chelate) 29 mg Other Ingredients: Microcrystalline Cellulose, Hypromellose (Natural Vegetable Capsule), and Magnesium Stearate. Does Not Contain: Gluten, yeast, artificial colors or flavors. Suggested Use Take 1 capsule per day or as recommended by your health care professional. Warning: If you are pregnant or nursing, consult your physician before taking this product. Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately. Storage: Keep out of the reach of children. More Info. Hemoglobin Concentration Reacted Iron is formulated with ferrous bisglycinate, an amino acid chelate form with a two-fold higher bioavailability than traditional iron salts (e.g., ferrous sulfate). A meta-analysis examining the effect of 4-20 weeks of iron supplementation concluded that ferrous bisglycinate supplementation improves hemoglobin concentration and causes minimal GI symptoms. In a 60-day randomized study of individuals with mild low-iron status, lower-dose ferrous bisglycinate (28 mg for 20 days followed by 14 mg for 40 days) had similar efficacy at increasing hemoglobin concentration compared to high-dose ferrous sulfate (105 mg for 60 days). Notably, compared with ferrous sulfate, participants taking ferrous bisglycinate reported fewer GI symptoms (42% and 17%, respectively). These findings highlight ferrous bisglycinate as an efficacious choice for supporting hemoglobin concentration with improved tolerability. Energy Balance Iron is a vital component in energy metabolism, serving as an important factor within the electron transport chain. Inadequate energy production is associated with fatigue. A meta-analysis of randomized controlled trials observed among adults with low iron status found that iron supplementation was associated with a reduction in subjective measures of fatigue. Additionally, a randomized controlled trial examining iron supplementation on symptoms of iron deficiency (i.e., restless legs, fatigue, poor sleep) reported improvements for all symptoms following treatment. Collectively, this evidence supports the role of iron supplementation in improving fatigue in select populations. Prenatal Support Several health organizations, including the World Health Organization and the National Institutes of Health, recommend iron supplementation during pregnancy to support maternal and fetal health. A 60-day randomized trial compared lower-dose ferrous bisglycinate (30 mg) with higher-dose ferrous sulfate (100 mg). The mean rise in hemoglobin concentration was significantly improved in the ferrous bisglycinate group with less GI upset.
