>Several Other Sizes Are Also Available. Please Inquire. Default Size: 200ugUpdated Date: Stock Protein updated on 20170405Research areas: OthersTarget / Protein: PdgfdBiologically active: Not TestedExpression system: E.coliSpecies of origin: Mus musculus (Mouse)Delivery time: 3-7 business daysUniprot ID: Q925I7AA Sequence: TPQRASIKALRNANLRRDESNHLTDLYQREENIQVTSNGHVQSPRFPNSYPRNLLLTWWLRSQEKTRIQLSFDHQFGLEEAENDICRYDFVEVEEVSESSTVVRGRWCGHKEIPPRITSRTNQIKITFKSDDYFVAKPGFKIYYSFVEDFQPEAASETNWESVTSSFSGVSYHSPSITDPTLTADALDKTVAEFDTVEDLLKHFNPVSWQDDLENLYLDTPHYRGRSYHDRKSKVDLDRLNDDVKRYSCTPRNHSVNLREELKLTNAVFFPRCLLVQRCGGNCGCGTVNWKSCTCSSGKTVKKYHEVLKFEPGHFKRRGKAKNMALVDIQLDHHERCDCICSSRPPRTag info: N-terminal 6xHis-SUMO-taggedExpression Region: 24-370aaProtein length: Full LengthMW: 56.2 kDaAlternative Name(s): Spinal cord-derived growth factor B Short name: SCDGF-B Cleaved into the following 2 chains: Platelet-derived growth factor D, latent form Short name: PDGFD latent form Platelet-derived growth factor D, receptor-binding form Short name: PDGFD receptor-binding formRelevance: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing (By similarity). Has oncogenic potential and can induce tumor formation. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of Extracellular domain matrix.Reference: "PDGF D, a novel protease-activated growth factor."LaRochelle W.J., Jeffers M., McDonald W.F., Chillakuru R.A., Giese N.A., Lokker N.A., Sullivan C., Boldog F.L., Yang M., Vernet C., Burgess C.E., Fernandez E., Deegler L.L., Rittman B., Shimkets J., Shimkets R.A., Rothberg J.M., Lichenstein H.S.Nat. Cell Biol. 3:517-521(2001)Purity: Greater than 90% as determined by SDS-PAGE.Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
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