Refresh Optive Mega-3 is Allergan's most advanced dry eye formula — a preservative-free, lipid-enhanced artificial tear that addresses all three layers of the natural tear film (lipid, aqueous, and mucin) simultaneously, rather than just replacing the aqueous layer like standard artificial tears. It is specifically formulated for patients with Meibomian Gland Dysfunction (MGD), evaporative dry eye, or any condition driven by a deficient or unstable lipid layer.Carboxymethylcellulose Sodium (CMC, 0.5%) provides aqueous layer lubrication. Glycerin (1.0%) provides humectant osmotic protection. Polysorbate 80 (0.5%) is the key differentiating active — it contains flaxseed-derived Omega-3 fatty acids (including ALA) that directly supplement and restore the lipid layer of the tear film, reducing the tear evaporation rate that is the primary driver of evaporative dry eye and MGD symptoms. This lipid-layer restoration is the mechanism that no standard artificial tear (which only adds water) can provide. The preservative-free, low-blur formula is suitable for daytime use and does not require shaking. Clinically proven to treat the signs and symptoms of dry eye. Remove contact lenses before use. FSA & HSA eligible. For external use only. Stop use and ask a doctor if eye pain, changes in vision, redness or irritation persist more than 72 hours. Available at Beauty Riche with same-day shipping.