Volumize. Rebuild. Renew. REGEN PDRN+ Crème is a first-of-its-kind volumizing crème that restores visible fullness, firmness, and hydration — powered by Lira Clinical's exclusive regenerative ingredient technology for clinical brightening results you can see and feel.This Crème Is For You If… You're experiencing visible volume loss, hollowness, or sagging in the skin Your skin feels chronically dehydrated or lacks that plump, bouncy texture You want a non-invasive alternative to support a fuller, more lifted appearance Dullness and uneven tone are concerns alongside aging You're ready to layer a regenerative moisturizer over an active serum routine Hero Ingredients Wild Salmon Stem Cell-CM — Clean, biomimetic marine cellular complexes with 4x more regenerative power than PDRN alone; boosts collagen repair and calms inflammation. PDRN (Polydeoxyribonucleotides) — Biocompatible salmon DNA that restores the extracellular matrix, moderates redness, and prevents sporadic hyperpigmentation. Adipofill'in™ (L-Ornithine) — Creates a non-invasive lipofilling-like effect, inflating adipocytes to restore lost volume and plumpness. EXO-tech (Exosomes) — Amplifies cellular communication to accelerate skin repair and renewal at the source. Copper Tripeptide-1 — Improves firmness and elasticity; antioxidant and anti-inflammatory with a speedy skin recovery effect. Chromabright™ — Inhibits melanogenesis to even skin tone, brighten, and protect against UV-induced aging. Kelp Extract — Immediate smoothing and tightening effect; natural polysaccharide that retains moisture and supports cellular function. Complete the RoutineLayer over the REGEN PDRN+ Serum for the full regenerative protocol — serum first to deliver actives deep, crème to seal in volume and hydration. Explore the complete Lira Clinical collection.
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