RenewGut+™ combines multiple mechanisms of action to support gut health, strengthen the gut lining, nurture the mucin layer, and promote optimal digestive function. RenewGut+™ is designed to work in conjunction with a probiotic (such as Multi-Biome™ or CoreBiotic®) by nourishing the gastrointestinal tract to foster a healthy environment for a thriving microbiome. Mechanisms of Action Fortifies gut lining and tight junctions to promote healthy intestinal mucosal barrier* Promotes healthy cytokine function* Provides healthy histamine support in the gut (both histamine absorption & degranulation)* Improves microbiome balance in the digestive tract* GI SUPPORT COMPLEX* RenewGut+™ is formulated to renew and optimize GI function. Mechanisms of Action Supports a healthy gut lining: Strengthens the gut lining and tight junctions, essential for preventing the translocation of harmful substances across the gastrointestinal barrier and promoting overall immune health* Improves mucin layer: Enhances mucin production, a crucial component of the protective mucus layer in the gut and vital for preventing harmful microbial activity and maintaining a healthy gut environment* Modulates cytokine activity: Promotes healthy cytokine activity in the gastrointestinal tract to decrease discomfort* Antihistamine action: Blocks H2 receptors, inhibits mast cell activity, and promotes healthy histamine levels for reduced gut distress* Supports the GI tract: Fosters a balanced gut environment for individuals managing their digestive challenges* Supports a healthy microbiome: Hydrolyzed collagen peptides and N-Acetyl D-glucosamine act as a prebiotic source, nurturing beneficial gut bacteria and supporting the production of short-chain fatty acids (SCFAs), essential for gut health, maintaining gut barrier function, and promoting a healthy immune response and overall well-being* Source of essential amino acids: Amino acids promote gut health by nourishing the intestinal lining and enterocytes, contributing to the restoration and maintenance of a healthy gut.* A healthy barrier between the digestive tract and bloodstream is essential for optimal nutrient absorption and to prevent toxins from entering the bloodstream. RenewGut+™ is designed to work in conjunction with a probiotic (such as Multi-Biome™ or CoreBiotic®) by promoting a well-functioning digestive system while also nourishing the gastrointestinal tract. RenewGut+™ is free from aloe vera (not recommended for long-term use) and glutamine (may lead to elevated glutamate and is linked to health challenges) and may be prescribed for long-term use. Instead, collagen peptides (Types I and III), high in glycine, proline, hydroxyproline, are the source of essential amino acids to promote gut healing. Features Constituents/ Actions Benefits* Hydrolyzed Collagen Peptides (Type 1 & 111) Source of essential amino acids Supports probiotic bacteria to strengthen the microbiome Aids in restoring the digestive tract lining Alleviates gastrointestinal discomfort N-Acetyl-D-glucosamine Enhances gut lining integrity by supporting the mucin layer of the GI tract Modulates cytokine levels Eases digestive distress RenewGut+ Blend™ GutGard® DGL (deglycyrrhized licorice) Supports gut lining and mucin layer health Acts as a demulcent to calm the digestive tract GutGard® is a patented version of DGL, with high levels of active flavonoids, requiring a smaller effective dose GutGard® has lower levels of glycyrrhizin, minimizing potential side effects Black Cumin (Nigella Sativa) Antihistamine support targeting histamine within the digestive tract Zinc Carnosine Fortifies tight junctions in the digestive lining Luteolin Reduces mast cell release of histamine Soothes gastric distress Modulates cytokine activity Supplement Facts / Dosing Ingredients RenewGut+™ Blend | 1900mg Hydrolyzed collagen peptides (type I & III), N-Acetyl D-glucosamine, GutGard® deglycyrrhized licorice, Black Cumin (Nigella sativa) (seed), Zinc Carnosine, Luteolin Zinc (from RenewGut+™ Blend) | 15mg Other Ingredients: Gelatin (capsule). Contains: Shellfish (shrimp) Manufactured without milk, eggs, fish, tree nuts, peanuts, sesame, wheat, soy and gluten. Produced in a facility that may process other ingredients containing these allergens. Suggested Use: As a dietary supplement, take 4 capsules once daily or as directed by your health care professional. Caution: Not for use by women who are pregnant or may become pregnant.