RT Advanced Electrospinning System – Industrial & Research Grade, Up to 8 Materials, 60 kV

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RT Advanced is a 60 kV industrial electrospinning system for unattended multi-material production: two fully independent spinning groups, up to 8 pumps, closed-loop thickness contr ol, an electrically insulated chamber, climate control precise to 10–70% RH ±2% and ambient–50 °C ±1 °C, and an audit trail designed to meet 21 CFR Part 11. It is built for laboratories and companies that need to move from experiments to repeatable production — including production that has to stand up to an audit. Two independent groups, one on each side of the collector RT Advanced is not one spinning station with more pumps bolted on. It is two complete, fully independent groups, each with its own 60 kV generator, its own four pumps, its own automatic needle cleaning and its own blow spinning system. The two groups sit symmetrically about the collector axis, and the collector itself acts as an electrostatic shield between them. That is what makes the architecture work: multi-emitter systems normally fight themselves, because jets repel each other and the field distorts. With the collector in the middle, each group works against a controlled potential rather than against the other group, and interference is minimised by geometry rather than corrected afterwards. Practically, it means the left side and the right side can run different materials, at different voltages, with different gas flows, depositing onto the same collector in a single run. Built for regulated environments Most electrospinning systems are research instruments. RT Advanced ships with the documentation set required to qualify the machine in a regulated production environment, and with the software controls an auditor expects to find. Named user accounts with role-based access. Every action is attributed to a person, not to a shared login. A complete audit trail, designed to meet 21 CFR Part 11. Parameter changes, run start and stop, alarms and interventions are recorded with user, timestamp and electronic signature — supporting pharmaceutical audits on both sides of the Atlantic. Alarms sent by email as they occur, so an out-of-range parameter or a fault does not go unnoticed between visits. Full process telemetry. Voltage, flow rates, gas flow, chamber temperature and humidity, collector speed and measured thickness are logged for every run. Qualification documentation for regulated environments, available on request. Your process data stays yours RT Advanced complies with the EU Data Act: you get free, secure, programmatic access to the machine’s configuration and telemetry data, and you can move it wherever you need — a cloud platform or a server inside your own network. Connectivity is built on Alleantia technology and supports more than ten integration protocols, so batch records and process data live in your systems rather than locked inside ours. For a validated process, that is the difference between a machine you can integrate and one you have to work around. The machine stops when the target is reached One or more laser sensors measure the deposit on the rotating collector in several positions while the run is in progress. RT Advanced does not just display that number — it acts on it: deposition continues until the target thickness is reached, then the machine stops on its own. Measuring in more than one position along the collector also tells you whether the deposit is uniform, not only how thick it is at one point. Fibres are too soft and thin for calipers or micrometers, so this is the only practical way to control thickness while the process runs. Eight materials, one deposit, no operator With eight independent programmable pumps across the two groups you can build structures no single-station system can reach: multilayer membranes, gradient scaffolds, blended mats, and core-shell fibers with coaxial needles. No competing system offers eight. Three features let it run overnight and over the weekend without anyone standing by: Automatic needle cleaning with timed jets of compressed gas, on each group. A clogged needle is the most common cause of an interrupted run. Closed-loop thickness control, so the run ends at the target rather than when someone comes back. Controlled atmosphere — temperature, humidity and inert gas flushing keep the process identical from the first hour to the last. In case of blackout or malfunction the system interrupts production automatically. Blow spinning, digitally controlled, on both groups An optional blow spinning module adds a gas flow that helps draw the jet. It raises throughput, and it lets you process solutions that will not open under electric field alone — more viscous, less conductive, or in solvent systems that resist electrospinning. It also runs with the high voltage off, as pure solution blow spinning. That is not a variant of the same process: it is a second technology on the same machine, and it covers polymers that electrospinning cannot handle at all. There is one blow spinning system per group, so the two sides can run different gas flows on different materials in the same run — or one side in electrospinning and the other in blow spinning. Gas flow is set digitally and measured with a Coriolis flow meter, which reads mass flow rather than volume — so the reading is unaffected by pressure and temperature, and the same setting gives the same result in January and in July. Most hybrid systems use a float meter and a hand valve. Because the flow is a digital parameter, it belongs to the recipe and to the telemetry, like voltage or solution flow rate. No tubes, no dead volume, no cross-contamination The collector stays fixed while the syringes move on the vertical axis. RT Advanced is the only system that moves the syringes without using tubes, and that has three consequences that matter in a regulated process: nothing is left behind in a tube between runs, there is no dead volume when you change material, and cross-contamination between materials is structurally prevented rather than managed by cleaning. It also means almost no solution is wasted at each material change — which matters when the polymer is expensive or available in milligrams. From a single sample to continuous production Flat or drum collectors from 1 to 250 mm in diameter and up to 500 mm long are replaced quickly thanks to a single-piece carrier. The collector rotates on a vertical axis, clockwise or anticlockwise, up to 5000 rpm without oscillation — which is what makes tubular structures with aligned fibres possible. The collector is insulated from ground and can be biased with its own generator when the process calls for it. For continuous output, a vertical-axis continuous belt produces flat substrates tens of metres long in a single run. Climate control, configured to your process Humidity is the parameter that most often makes a recipe work in one season and fail in another, and different processes need it controlled in different directions. Our external air treatment unit (UTA) connects directly to RT Advanced and is configured around your process: vaporisers when humidity has to be added, a chiller when it has to be removed, plus heating, heating and cooling, or drying stages as required. In its full configuration the UTA holds relative humidity between 10 and 70% to within 2% and temperature from ambient up to 50 °C to within 1 °C. What sets it apart is not those numbers on their own — it is holding them while extracting solvent vapour. Most systems treat the two as alternatives: either you seal the chamber to stabilise the climate, or you ventilate it and lose control of humidity. The UTA does both, with a controlled airflow strong enough to prevent solvent stagnation and gentle enough not to drag the nanofibres off the collector. You keep a stable process, a safe atmosphere and the fibres you produced. An insulated chamber, because grounded metal steals fibres The entire internal surface of the chamber is made from electrically insulating materials. Competing systems use metal components and structures which, by construction, have to be earthed — and earthed metal near a high voltage field attracts nanofibres continuously. Those fibres are lost yield: they never reach the collector, and their absence changes what does. Insulating the chamber removes that loss at the source rather than compensating for it, which is why the same solution yields more usable material per run and a more consistent deposit. Pumps that work at 60 kV, continuously In RT Advanced the syringes themselves sit at high potential and the pumps operate safely and continuously at up to 60,000 V — as far as we know, the highest figure available on the market for needle-based electrospinning systems. This is what makes it possible to move the syringes with the needles instead of feeding them through tubes, and it widens the range of polymers and solvent systems you can process, since the field is no longer the limiting factor. A thermal map, not just a set-point What a set-point does not tell you is how uniform the temperature is around the collector, where the fibres actually form — a region you cannot easily instrument without disturbing the process. So we modelled it: finite element analysis of the chamber shows the temperature distribution around the vertical collector, and the deposition volume sits in a uniform region. We share the analysis on request. The simulation is an analysis, not a measurement, and we do not present it as one. It is how we designed the airflow, and it is why we can explain — rather than assert — why results stay consistent along the collector. Support that keeps you compliant Warranty extensions up to five years. Scheduled maintenance plans, designed to support your own regulatory obligations rather than only to fix faults. A dedicated remote assistance module, so most process and control issues are resolved without waiting for a visit. Direct access to our R&D team in Pisa — the people who built the machine. Technical specifications Two fully independent spinning groups, symmetrically placed about the collector axis, which acts as an electrostatic shield. One 60 kV high voltage generator per group. Four pumps per group — up to 8 independent syringes in total. Automatic needle cleaning with timed jets of compressed gas, on each group. Optional blow spinning module, one per group: digital gas flow control with Coriolis mass flow measurement; operates with or without high voltage. Multi-needle or coaxial needle system. Flat or drum collectors, 1 to 250 mm in diameter, maximum length 500 mm. Collector rotation clockwise or anticlockwise, vertical axis up to 5000 rpm. Collector insulated from ground, connectable to its own high voltage generator. Continuous belt for flat substrates up to tens of metres. External air treatment unit (UTA) with vaporisers, chiller, heating, heating/cooling and drying stages configured to the process. UTA full configuration: 10–70% RH ±2%, ambient to 50 °C ±1 °C, with simultaneous solvent extraction. Inert gas flushing. Chamber internal surfaces in electrically insulating materials — no earthed metal attracting fibres. Syringe pumps operating continuously at up to 60 kV. Closed-loop thickness control with one or more laser sensors (optional). Built-in suction system. Access and visibility on three sides of the spinning chamber. Industrial tablet-PC with WiFi control. Omron industrial components for the control electronics. General Unit Value Note Depth mm 1035 Height mm 2200 Width mm 1050 Total weight kg 400 approx. Max power consumption kW 1.5 – 4 depending on options installed Supply voltage V AC 230 single phase 50-60 Hz High voltage generators 2 × 60 kV one per spinning group Ventilation system Yes Humidity control % RH 10 – 70 ±2%, UTA full configuration Temperature control °C ambient – 50 ±1 °C, UTA full configuration Warranty 1 year extensions available up to 5 years Safety Opening of the spinning chamber is blocked when high voltage is present. Automatic interruption of production in case of blackout or malfunction. Active control system to eliminate sparks and high voltage discharges. Producing medical devices in a cleanroom? A dedicated version of RT Advanced is available for medical device manufacturing: washable stainless steel external structures, automatic mandrels inside the chamber, and an anthropomorphic robotic arm outside, so scaffolds and grafts are produced in a fully automated, clean island. Geometries are customised to the application. Talk to us about the cleanroom configuration Not sure how your material should be spun? Describe your polymer and target fiber, and our AI assistant will suggest the process parameters to start from - solvent system, voltage, flow rate, distance and collector setup. DISCOVER HOW TO SPIN YOUR MATERIAL WITH ESPIN.AI One electrospinning ecosystem, from first experiment to validated production. RT Advanced is where a project ends up once it needs to run unattended and pass an audit — the same modular platform that starts on All In One, backed by 400+ installations, 124 peer-reviewed publications and customers in 70+ countries. Which complete system fits your project? RT Advanced is the top of our range. Every Linari machine is delivered as a complete, ready-to-run system - chamber, generator, pumps, needles and collectors included - so the choice is only about scale and level of automation. RT AdvancedMulti-material & unmanned Two independent groups, 2 × 60 kV, 8 pumps, controlled atmosphere, automatic needle cleaning and closed-loop thickness control. For multilayer and gradient structures, and for production that runs unattended. Pure SpinnerBulk substrate-free fibre The same architecture on a horizontal axis, for when the nanofiber itself is the product - additives, inks, chopped fibres. Drum up to Ø250×600 mm (0.47 m² of collecting area), up to 140 needles, and blow spinning with or without high voltage. All In OneModular R&D platform 40 kV multi-collector system that grows with your research: roll-to-roll up to 300 mm, XY gantry, external air treatment unit. The natural choice when the budget is not yet industrial but the ambition is. Gantry 3D SpinProgrammed trajectories G-code XY control of the needle path from CAD, or CSV from a spreadsheet, with control of the needle-to-collector distance during the run. Compact UnitSmallest complete system Random and aligned fibers with a moving spinneret and rotary collector up to Ø80×300 mm, in a reduced footprint. Not sure which one? Talk to an R&D expert and we will configure the system around your material and your target output - or have our laboratory in Pisa validate your nanofiber first. Frequently asked questions What does "two independent groups" mean in practice? Each group has its own 60 kV generator, four pumps, automatic needle cleaning and blow spinning system. The two sit symmetrically on either side of the collector, which acts as an electrostatic shield between them. You can run different materials, voltages and gas flows on the two sides in the same run, depositing onto the same collector. Can RT Advanced really run without an operator? Yes. Automatic needle cleaning with timed compressed-gas jets on both groups, controlled temperature and humidity, and closed-loop thickness control allow long unattended productions, including overnight runs: the machine stops when the target thickness is reached. How many materials can it spin at the same time? Up to eight, on eight independent, fully programmable pumps split across the two groups, so you can build multilayer membranes, gradient scaffolds and blended mats in a single run, and work with coaxial needles for core-shell fibers. Can it do blow spinning as well as electrospinning? Yes, with the optional module, and there is one system per group. A digitally controlled gas flow can be combined with the electric field as electro-blow spinning, to raise throughput and to process solutions that will not open under field alone; or the high voltage can be switched off entirely for pure solution blow spinning, which covers polymers electrospinning cannot handle. Flow is measured with a Coriolis mass flow meter, so it is unaffected by pressure and temperature and is logged as part of the recipe. Is RT Advanced suitable for a regulated production environment? Yes. It provides named user accounts with role-based access, a complete audit trail with electronic signature designed to meet 21 CFR Part 11, and full process telemetry for every run. Qualification documentation is available on request, and scheduled maintenance plans are designed to support your own regulatory obligations. Can I access the machine data from my own systems? Yes, and free of charge. RT Advanced complies with the EU Data Act: configuration and telemetry data are available through secure programmatic access, built on Alleantia technology with more than ten integration protocols, so you can write batch records straight into your cloud platform or internal servers. Why is the absence of tubes important? The syringes move with the needles, so there are no flexible tubes between them. Nothing is left inside a tube at the end of a run, which avoids wasting solution, removes the need to replace tubes regularly, and structurally prevents cross-contamination between materials. How accurate is the thickness measurement? The optional laser measuring system based on Omron optical technology measures fiber thickness in real time with an accuracy of 10 nanometers, since calipers and micrometers cannot measure such soft, thin deposits. One or more sensors can be used to check uniformity along the collector, and the machine stops deposition when the target is reached. Can it produce tubular structures with aligned fibers? Yes. The collector rotates on a vertical axis up to 5000 rpm without oscillation, which is what allows tubular structures with aligned fibers. A continuous belt option is also available for flat substrates up to dozens of meters long. What size collectors does it accept? Flat or drum collectors from 1 to 250 mm in diameter, up to 500 mm long, replaced quickly thanks to the single lower self-centering chuck. The collector is insulated from ground and can be connected to its own high voltage generator. Is there a system with an even larger collecting area? Yes. If your priority is the amount of material produced per run rather than the number of materials, Pure Spinner takes drum collectors up to 250 mm in diameter and 600 mm in length - 0.47 m² of collecting area - on a horizontal axis, with up to 140 needles and an optional blow spinning module. How do I know if my material can be electrospun? You can ask espin.ai for a starting set of process parameters, or have our laboratory in Pisa run a feasibility test on your material and characterize the fibers by SEM before you decide. Download Datasheet Show more