Description S-Adenosyl methionine (S-Adenosyl methionine, SAM) is an auxiliary substrate involved in the methyl transfer reaction, which in the body is composed of adenosine triphosphate and methionine in the methionine adenosyltransferase under the action of synthesis. SAM is prepared in a solution of 10 mM HCl, 10% Ethanol, and pH 4 at 25℃. This product is produced by GMP process requirements and provided in liquid form. Features Validated, product-specific processes and analytical methods Product-specific stability Documentation follows applicable GMP guidelines AOF production process and raw materials (TSE & BSE) Nitrosamine statement Regulatory support documents available Large-scale production Applications Enzymatic capping process for mRNA vaccines and therapeutics Enzymatic methylations of biopolymers Specifications CAS No 485-80-3 Formula C15H23N6O5S+ Molecular Weight 399.44 g/moL Purity (HPLC) ＞ 90% Content 32 mM ± 2 mM Composition (1X) 10 mM HCl, 10% Ethanol pH 4 at 25℃ Structure Components Components No. Name 10619ES02 10619ES25 10619ES50 10619ES76 10619 S-adenosylmethionine (SAM) GMP-grade (32 mM) 0.5 mL 25 mL 50 mL 500 mL Shipping and Storage The product is shipped with dry ice and can be stored at -15℃ ~ -25℃ for one year. Figures Purity Assessment Figure 1. The purity (HPLC) of SAM product could be over 98% (Figure 1A) and the optical purity（ee, %）of (S, S) -SAM isoform always be about 70% (Figure 1B). Documents: Safety Data Sheet MSDS-10619-S-adenosylmethionine (SAM) GMP-grade (32 mM)-HB220701.pdf Manuals 10619_Manual_HB221110_EN.pdf
