Product overview S-Adenosyl Methionine (SAM-e) is produced by the body from ATP and the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAM-e is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAM-e is also required for the synthesis of critical neurotransmitters and hormones. Supports mood, overall cognitive health and sleep. Biological compound found in every cell in the body. Supports the metabolism of major brain neurotransmitters. Only the best Doctor's Best SAM-e uses Italian Soloesse® SAM-e in their products, which supports slow and targeted release for GI tolerance and absorption. SAM-e has been shown to support mood, brain health and mental focus. It is essential for the healthy metabolism of the major brain transmitters' dopamine, serotonin and norepinephrine. In addition, SAM-e supports joint comfort and mobility as well as supporting liver health and detoxification. SAM-e effectiveness has been published in 18 controlled human studies published over 40 years. Doctor's Best SAM-e uses pharmaceutical grade materials. SAM-e is optimized for potency, stability, and to survive the stomach acid and reach the intestine (where it is absorbed) Ingredients SAM-e (S-Adenosyl-L-Methionine disulfate p-toluenesulfonate) 200 mg. Other ingredients: Microcrystalline cellulose, stearic acid, magnesium silicate, calcium chloride anhydrous, flake shellac dewaxed, magnesium stearate, magnesium hydroxide, glycerol, silica, arginine base, sodium alginate, calcium oxide.Does not contain: GMO, Gluten, Soy Suggested Use Recommended intake: Suggested Adult Use: Take one tablet, twice daily between meals, or as recommended by a healthcare practitioner. Do not chew or crush tablet. Cautions Individuals using antidepressant medications should consult with their healthcare practitioner prior to using this product. Individuals diagnosed with Bipolar Disorder should avoid supplementing with SAM-e. Do not use if pregnant or breastfeeding. May cause gastrointestinal discomfort in a small percentage of people. Store in a cool dry place. Do not use if safety seal is broken or missing. Keep out of reach of children. Always read the label and use as directed. If symptoms persist see your healthcare practitioner.
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