Doctor's Best SAM-e may help support mood, brain health, and mental focus and it is essential for the healthy metabolism of the major brain transmitters' dopamine, serotonin, and norepinephrine. In addition, SAM-e supports joint comfort and mobility as well as supporting liver health and detoxification. SAM-e effectiveness has been published in 18 controlled human studies published over 40 years. S-Adenosyl Methionine (SAM-e) is produced by the body from ATP and the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAM-e is involved in numerous biochemical reactions in tissue including the liver, joints, and brain. SAM-e is also required for the synthesis of critical neurotransmitters and hormones. Doctor's Best SAM-e uses pharmaceutical grade materials. SAM-e is optimized for potency, stability, and to survive the stomach acid and reach the intestine (where it is absorbed).
