Key Benefits: Natural & Effective: Contains 100% natural kelp, sustainably harvested from the pristine waters off the Scandinavian coastline. Clinically Studied: Trials show significant reduction in plaque and tartar, while also improving bad breath. VOHC Accepted: Trusted by veterinarians for promoting good oral health in dogs. Visible Results: Noticeable improvement in 3-8 weeks when used as directed. Convenient Packaging: Available in a handy 60g, 180g and 420g. Made in the USA: High-quality product manufactured in the United States. NEW LOOK - SAME GREAT PRODUCT! ProDen PlaqueOff® Powder is a oral health supplement containing the natural and organic kelp ingredient A.N ProDen® - shown in clinical trials to help reduce plaque and tartar and to help improve bad breath. The results are usually seen between 3 to 8 weeks, with continued use. For a 10kg dog, a 60g bottle lasts roughly 6 months.