NOTE: This product has been discontinued. YOUR CHALLENGE You want to improve your research using a relevant microenvironment for your cells, however the variety of products on the market is huge. To find out which one is the best for you is both time consuming and costly. You don’t want to test out multiple products and waste time reading lengthy protocols. Ideally, you want a product that provides you with biologically relevant microenvironments for your cells and reproducible results. A simple tool to find the best environment for any cell type We provide you with the ideal tool to rapidly test a large variety of cell microenvironments at once. denovoMATRIX technology allows us to incorporate the most important biological ligands for cell adhesion, spreading and robust growth within our biomimetic coatings. We have compiled 96 coating compositions which represent 96 different microenvironments in the screenMATRIX. Find out which biological ligands are responsible for cell adhesion, differentiation or changes in your cell phenotype. Turn pipetting into publications, and interest into insight. Format 5X 96-well precoated plates The screenMATRIX is assembled using the glycosaminoglycan sugars (GAGs) dextran sulfate, heparin, chondroitin and dermatan. With the exception of the synthetic dextran sulfate, these molecules are naturally present in the extracellular matrix (ECM) and have important roles in signaling as well as growth factor binding. Peptides, which mimic various ECM proteins, complete the composition of the screenMATRIX. Some recapitulate important ECM adhesion proteins such as fibronectin, vitronectin, laminin and collagen, others mimic signaling proteins such as bone morphogenic protein, fibroblast growth factor and transforming growth factor (among others). Video on screenMATRIX Ready to use, fast and efficient The screenMATRIX is ready to use without any preparation. All you need to do is seed your cells on the screenMATRIX and discover which coating works best. Check out our screenMATRIX info sheet to find out exactly which biological ligands are responsible for your optimal cell response. Resources screenMATRIX Product Info Sheet and Cell-Seeding Protocol screenMATRIX Material Safety Data Sheet (MSDS) screenMATRIX Application Note: AI-assisted Imaging Accelerates Selection of Optimal Cell Culture Matrices Product References Tondera, Christoph et al. “Highly Conductive, Stretchable, and Cell-Adhesive Hydrogel by Nanoclay Doping.” Small (Weinheim an der Bergstrasse, Germany) vol. 15,27 (2019): e1901406. doi:10.1002/smll.201901406 Panella, Stefano et al. “Chemically Defined Xeno- and Serum-Free Cell Culture Medium to Grow Human Adipose Stem Cells.” Cells vol. 10,2 466. 22 Feb. 2021, doi:10.3390/cells10020466 Found your ideal coating? Get your favorite coating in a format of your choice – your customMATRIX Did you find one or multiple microenvironments strongly performing in your cell culture? Let us know. The denovoMATRIX system is extremely scalable and modular. Get your favorite cell culture plasticware format with a coating of your choice or combine multiple coatings into your own special customMATRIX.
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