NeuroScience SeroTrex Chewable tablets containing L-theanine, an amino acid shown to reduce stress, promoting balance. The Science: Glutamate The primary excitatory neurotransmitter in the brain Glutamatergic signaling underlies mechanisms related to anxiousness and stress You may also be interested in GABA Trex. Ingredients Serving Size: 2 Chewable Tablets Amount/Serving Calories 5 Total Carbohydrate 2 g Total Sugars 0 g Xylitol 2 g L-theanine 200 mg 5-hydroxytryptophan (from Griffonia simplicifolia seed extract) 60 mg Other Ingredients: Stearic acid, citric acid, magnesium stearate, natural orange flavor, and stevia extract (Stevia rebaudiana)(leaf)(Rebaudioside A). Suggested Use Chew 1-2 tablets up to two times daily or as directed by your healthcare provider. Do not exceed the suggested use. Warning: If you are pregnant or nursing, consult your healthcare provider before use. Keep out of reach of children. Storage: This product has a tamper-evident seal under the cap. Do not use if the seal is broken or missing. Store at room temperature, in a dry place. More Info. Glutamate, anxiousness, and stress Glutamate is associated with anxiousness and stress Stress activates the hypothalamus-pituitary-adrenal (HPA) axis, which releases glucocorticoids that affect brain function Studies have shown that the brains of both pediatric and geriatric populations are particularly susceptible to stress L-theanine acts as a glutamate receptor antagonist L-theanine binds to glutamate receptors (AMPA, kainate, and NMDA receptors) and blocks the binding of glutamate to its receptors L-theanine improves sleep efficiency The effects of L-theanine were assessed in randomized, double-blind, placebo-controlled studies In individuals 8-12 years of age, L-theanine (200 mg) twice daily (morning and afternoon) significantly increased sleep efficiency (percentage of night spent sleeping restfully) and reduced nocturnal motor activity In adults, single administration of L-theanine (200 mg) significantly reduced feelings of stress under mental strain
