Kobayashi Shoyo Medicated Toothpaste — Gum Care & Periodontal Formula, 100 g Kobayashi Shoyo is a 医薬部外品 (quasi-drug) medicated toothpaste from Kobayashi Pharmaceutical Co., Ltd. — one of Japan's most trusted healthcare and OTC pharmaceutical manufacturers. The formula combines five natural plant-derived active ingredients targeting the most common cause of adult tooth loss: periodontal (gum) disease. With Hinokitiol from Hinoki cypress as its signature antibacterial, Dipotassium Glycyrrhizate from licorice root as an anti-inflammatory, and Aluminum Lactate as a gum-tightening astringent, Shoyo targets gum health comprehensively while providing pleasant herb-mint freshness. See also: Japanese Oral Care | Japanese Health & Wellness | Daiichi Sankyo Clean Dental N Key Benefits ✓ Hinokitiol (β-Thujaplicin) — natural antibacterial derived from Hinoki cypress (檜) wood; inhibits Streptococcus mutans and periodontal bacteria with a long history of use in Japanese oral care ✓ Dipotassium Glycyrrhizate — anti-inflammatory compound from licorice root (甘草); soothes inflamed, bleeding gums ✓ Aluminum Lactate — astringent that tightens and firms gum tissue, reducing pocket depth ✓ Potassium Nitrate — addresses tooth sensitivity by calming dental nerve signal transmission ✓ β-Glycyrrhetinic acid (GK-2) — additional natural anti-inflammatory for deep gum tissue soothing ✓ Sodium Monofluorophosphate (NaMFP) — fluoride source for cavity prevention alongside gum care ✓ 5 natural plant extracts — Ginseng, Turmeric, White Birch, Peony, and Angelica Root Product Details Brand Kobayashi Pharmaceutical Co., Ltd. (小林製薬株式会社) Country of Origin Japan Product Type Medicated Toothpaste (Quasi-Drug / 医薬部外品) Format Paste in tube Net Weight 100 g JAN 4987072027110 Quasi-Drug Status 医薬部外品 — regulated active ingredients under Japan's MHLW Fragrance Herb-mint type Who Is This For? ✓ Adults experiencing gum inflammation, bleeding gums, or early periodontal symptoms who want a daily-use medicated toothpaste specifically targeting gum health ✓ People with tooth sensitivity who also want comprehensive gum-protective benefits beyond standard sensitive formulas ✓ Adults 40+ aware of increased periodontal risk wanting a proactive, plant-based gum-care routine ✓ Fans of Japanese medicated oral care looking for authentic quasi-drug toothpaste rarely available outside Japan ✓ Those preferring plant-derived actives — Hinoki cypress, licorice, ginseng, turmeric — over purely synthetic antibacterials How to Use Squeeze approximately 1–1.5 cm of paste onto a toothbrush. Brush all tooth surfaces including the gum line for 2–3 minutes. Pay particular attention to the gum–tooth junction where periodontal bacteria accumulate. Rinse mouth minimally with water — rinsing less preserves fluoride on tooth surfaces (Japanese dentist guidance). Use twice daily: morning and before bed. Frequency: Twice daily for best gum-protective and cavity-prevention results. Active Ingredients & Full Formula Quasi-drug actives (with regulatory status under Japan's MHLW): Hinokitiol (β-Thujaplicin) — antibacterial Dipotassium Glycyrrhizate — anti-inflammatory Aluminum Lactate — gum-tissue astringent Potassium Nitrate — sensitivity reduction β-Glycyrrhetinic Acid (GK-2) — anti-inflammatory Sodium Monofluorophosphate (NaMFP) — fluoride / cavity prevention Inactive / base ingredients (selected): Purified Water, Propylene Glycol (PG), Ethanol, Aluminum Hydroxide (abrasive), Sorbitol Solution (humectant), Concentrated Glycerin, Anhydrous Silicic Acid (base), Sodium Lauroyl Methyl Taurate (surfactant/foaming), Hydroxyethyl Cellulose, Xanthan Gum (thickeners), Ginseng Extract, Turmeric Extract, White Birch Extract, Peony Extract, Angelica Root Extract, Herb-mint flavour, pH adjusters, stabilisers. Full ingredient list on Japanese label is authoritative. JAN 4987072027110. Cautions ⚠️ This is a quasi-drug medicated product — if using other medicated oral care products, check for ingredient interactions. ⚠️ Do not swallow. Rinse thoroughly if swallowed accidentally. Keep out of reach of children. ⚠️ If mouth sores, open wounds in the mouth, or severe oral irritation are present, consult a dentist before use. ⚠️ If gum bleeding, pain, or inflammation worsens, discontinue and see a dental professional — medicated toothpaste addresses early-stage gum issues but does not replace professional dental treatment. ⚠️ Avoid contact with eyes. If contact occurs, rinse immediately. ⚠️ Contains Ethanol (alcohol) — if you have concerns about alcohol-based ingredients for religious reasons, please check the formula. This product is not intended to diagnose, treat, cure, or prevent any disease. For professional dental guidance consult your dentist. Package Contents 1 × Kobayashi Shoyo Medicated Toothpaste, 100 g tube Shipping & Store Notes Ships directly from Japan Processing time: 2–6 business days Tracking number provided after dispatch Import duties and taxes may apply depending on destination country Opened cosmetics and supplements cannot be returned for hygiene and safety reasons Authenticity Guarantee We are based in Kobe, Japan, and ship all products directly from our Japanese warehouse. Kobayashi Shoyo toothpaste you receive is genuine, sourced directly from Japanese retail channels — the authentic quasi-drug version sold in Japanese pharmacies. Frequently Asked Questions What is 医薬部外品 (quasi-drug) and why does it matter for toothpaste? In Japan, 医薬部外品 is a regulated category between a cosmetic and a pharmaceutical drug. A quasi-drug toothpaste contains active ingredients — like Hinokitiol, fluoride compounds, or anti-inflammatories — at concentrations approved by Japan's Ministry of Health, Labour and Welfare (MHLW) to have measurable health effects (antibacterial, anti-inflammatory). This is stronger than a standard "cosmetic" toothpaste, but not as strictly regulated as a prescription pharmaceutical. What is Hinokitiol and why is it special? Hinokitiol (β-Thujaplicin) is a natural compound derived from the wood of Hinoki cypress (Chamaecyparis obtusa), Japan's revered native timber tree. It has demonstrated antibacterial properties against a range of oral bacteria, including Streptococcus mutans (cavity-causing) and periodontal pathogens, in published research. It is a signature ingredient in premium Japanese oral care products and is rarely found in Western toothpastes. Can Shoyo toothpaste replace my regular toothpaste? Yes. Kobayashi Shoyo is designed for twice-daily use as your primary toothpaste. It provides both gum-care actives and cavity prevention (fluoride via NaMFP), so there is no need to use a second toothpaste alongside it. For best results, brush for 2–3 minutes and rinse minimally to keep fluoride in contact with enamel. Does this toothpaste foam normally? Kobayashi Shoyo foams moderately due to its Sodium Lauroyl Methyl Taurate surfactant — a gentler amino acid-derived foaming agent compared to SLS (Sodium Lauryl Sulfate). The foam is sufficient for thorough cleaning without excessive bubbling. This makes it suitable for those who find high-foam toothpastes irritating. Is Kobayashi Shoyo suitable for children? Kobayashi Shoyo is formulated for adult use. Children should use age-appropriate toothpastes with lower fluoride concentrations and without the medicated quasi-drug actives (Potassium Nitrate, Aluminum Lactate) not intended for developing dentition. For children's oral care, consult a paediatric dentist for the appropriate product.
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