Prescription Vasodilator Tablets for Pulmonary Hypertension in Dogs and Cats Product Description Sildenafil 100 mg tablets are prescribed off-label for dogs and cats to treat pulmonary arterial hypertension, a condition where blood pressure in the lung arteries climbs to dangerous levels. It works by relaxing and widening the lung's blood vessels, taking the strain off the right side of the heart. In dogs, it is also used for megaesophagus and myxomatous mitral valve disease. Benefits Pulmonary Pressure Reduction: Reduces elevated lung artery pressure by relaxing vessel walls, easing strain on the right side of the heart. Improved Exercise Tolerance: Improves energy and exercise tolerance in dogs and cats with pulmonary hypertension caused by heart or lung disease. Megaesophagus Support: Relaxes the lower oesophageal muscle in dogs with megaesophagus, allowing food to pass into the stomach more easily. Quality of Life Support: Reduces breathlessness and fatigue in pets with pulmonary hypertension, supporting a better overall quality of daily life. Mitral Valve Disease Aid: Also used in dogs with myxomatous mitral valve disease as part of a broader cardiac management plan. Ingredients Active Ingredients Sildenafil 100 mg per tablet How to Use Sildenafil is a prescription-only medication. A valid veterinarian prescription is required to purchase this product. Please follow your veterinarian's specific instructions for the dosage and administration of this medication for your pet. Disclaimer: Dosage and administration of this medication must be determined by a licensed veterinarian. Always consult your veterinarian before administering or adjusting any prescription medication for your pet. Sildenafil tablets can be crushed and mixed into a treat or small portion of food to make administration easier. Just ensure your pet eats the full amount to receive their complete dose. Shop Pill Pockets for Dogs | Shop Pill Pockets for Cats Additional Information Precautions Avoid in Allergic Pets: Do not use in pets with a known allergy to sildenafil or any related phosphodiesterase inhibitor class medications. Hypotension Caution: Use with extreme caution in pets with resting hypotension, as sildenafil can dangerously lower blood pressure levels further. Fluid Depletion Risk: Avoid in severely dehydrated or fluid-depleted pets, as further blood pressure reduction may lead to sudden collapse. Cardiac Obstruction Caution: Use with caution in pets with severe left ventricular outflow obstruction; always consult your vet before starting treatment. Drug Interactions: Tell your veterinarian about all current medications before starting sildenafil, as interactions with other cardiac drugs are possible. Autonomic Dysfunction: Pets with autonomic dysfunction or known bleeding disorders require very close veterinary supervision throughout sildenafil treatment. Food Timing Guidance: Generally give on an empty stomach; if digestive upset occurs, consult your veterinarian before making any dosing changes. Possible Side Effects Vomiting: Vomiting may occur and should be reported to your veterinarian if it becomes frequent or persistent during treatment. Diarrhoea: Loose stools or diarrhoea are possible; contact your veterinarian if gastrointestinal symptoms persist or worsen during therapy. Reduced Appetite: Reduced appetite has been noted in some pets receiving sildenafil; inform your vet if it continues or worsens. Skin Flushing: Skin flushing, particularly around the groin or belly, may be visible in some dogs following sildenafil administration. Overdose Signs (Serious): Signs of overdose including weakness, collapse, or very low blood pressure require immediate emergency veterinary care without delay. Storage Information Room Temperature Storage: Store tablets at a controlled room temperature between 67°F and 77°F, away from direct sunlight and heat sources. Protect from Moisture: Keep the container tightly sealed at all times to protect tablets from moisture and light exposure during storage. Keep Out of Reach: Store out of reach of children and pets at all times to prevent accidental ingestion or unintended exposure. NOTE: For generic medications, the product image shown may not reflect the actual item received. Generic medications can vary in size, color, and shape between orders depending on the manufacturer. Additionally, your medication may arrive packaged in a HardyPaw Pharmacy vial. Shipping & Return We offer ground, express, and priority delivery; see our shipping policy for details. For return instructions or product concerns, please refer to our detailed refund policy. Prescription items are NON-RETURNABLE and NON-REFUNDABLE. Frequently Asked Questions Q1: What is sildenafil 100 mg used for in dogs and cats? Ans: Sildenafil is used off-label in dogs and cats to treat pulmonary arterial hypertension, a condition where blood pressure in the lung arteries is dangerously elevated. In dogs, it is also prescribed for megaesophagus and myxomatous mitral valve disease management under veterinary guidance. Q2: How long does sildenafil take to work in dogs and cats? Ans: Sildenafil typically begins acting within one to two hours of administration in dogs and cats. A noticeable improvement in clinical signs such as reduced breathlessness or improved energy levels may take several days of consistent daily treatment to become clearly apparent. Q3: Should sildenafil be given with or without food? Ans: Sildenafil is best given on an empty stomach for faster absorption. If your pet vomits or seems uncomfortable after a dose, check in with your vet, as they may suggest giving it with a small amount of food to ease the upset. Q4: What are the signs of sildenafil overdose in pets? Ans: Signs of a sildenafil overdose include a sudden drop in blood pressure, weakness, vomiting, a racing heart, and collapse. If any of these show up after dosing, stop the medication straight away and get your pet to an emergency vet or contact a pet poison helpline immediately. Q5: Is sildenafil safe for use in cats? Ans: Yes, sildenafil has been studied in cats and is generally considered safe when prescribed and supervised by a veterinarian. It is used less commonly in cats than in dogs, and close monitoring for side effects and treatment response is especially important in feline patients.
