SkinCeuticals A.G.E. Interrupter Advanced is the next-generation anti-glycation cream — a physician-dispensed, clinically validated moisturizer formulated with 18% concentrated Proxylane™, 4.25% wild fruit flavonoid blend (blueberry and pomegranate extracts), and 0.1% glycyrrhetinic acid. Clinically proven to smooth visible lines and wrinkles across five facial zones typically targeted by aesthetic procedures, while simultaneously addressing glycation — the sugar-induced cross-linking process that damages collagen and elastin and accelerates aging.Proxylane™ is SkinCeuticals' patented hydroxysaccharide molecule derived from beech wood xylose — a structural analogue of xylose that anchors to CSPG (chondroitin sulfate proteoglycans) in the dermal matrix to stimulate collagen, fibronectin, and glycosaminoglycan synthesis. At 18% concentration, it delivers the highest anti-glycation and pro-collagen stimulus available in this product class. Wild fruit flavonoids from blueberry and pomegranate extracts defend against UV-induced glycation, reduce oxidative glycation byproduct formation, and protect existing collagen and elastin. Glycyrrhetinic acid provides anti-inflammatory and skin-tone-supporting activity. Niacinamide soothes and improves skin tone. Adenosine supports skin firmness and the skin's natural repair cycle. Available at Beauty Riche — authorized SkinCeuticals retailer with same-day shipping.