Neurotransmitter & Sleep Hormone Test Advanced Brain Fog, Stress, Anxiety, Sleep & Mood Analysis | 42 Biomarkers The Neurotransmitter & Sleep Hormone Test is an advanced at-home laboratory assessment designed to evaluate neurotransmitter balance, stress hormone function, cortisol rhythm, sleep hormone melatonin production, mood regulation, sleep quality, and neuroendocrine health. This comprehensive profile combines advanced LCMS neurotransmitter testing with diurnal cortisol and melatonin analysis to provide deeper insight into how stress, hormones, and brain chemistry may affect your physical and emotional wellbeing. The test includes 42 biomarkers and is suitable for both adults and children. What Does This Test Measure? This advanced profile analyses: Neurotransmitters Chemical messengers that influence: Mood Anxiety Motivation Focus Memory Sleep Cognitive performance Emotional wellbeing Stress Hormones Assessment of: Free Cortisol Free Cortisone Daily cortisol rhythm Stress response patterns Sleep Hormones Melatonin metabolite analysis to evaluate: Sleep-wake cycles Circadian rhythm function Sleep quality 42 Biomarkers Included Neurotransmitter Markers Includes advanced LCMS analysis of: Serotonin (5-HT) Dopamine (DA) GABA Norepinephrine Epinephrine Glutamate Histamine Glycine Taurine Tyrosine Kynurenine Pathway Markers Additional neurotransmitter metabolites Diurnal Hormone Markers Free Cortisol ×4 Free Cortisone ×4 6-Sulfatoxymelatonin (MT6s) ×4 Creatinine ×5 Why Neurotransmitter Testing Matters Neurotransmitters are essential chemical messengers used by the nervous system to communicate between nerve cells and regulate important body functions. Neurotransmitter imbalances may influence: Anxiety Depression Brain fog Stress tolerance Sleep quality Fatigue ADHD-related symptoms Mood swings Focus and concentration Emotional wellbeing This test helps identify possible biochemical imbalances that may contribute to ongoing symptoms and poor mental performance. Symptoms This Test May Help Investigate Mood & Mental Health Anxiety Depression Mood swings Panic attacks Irritability Emotional instability OCD-related symptoms Cognitive & Brain Health Brain fog Poor concentration Forgetfulness ADHD-related symptoms Mental fatigue Memory difficulties Stress & Adrenal Symptoms Burnout Chronic stress Fatigue Poor stress tolerance Nervousness Sleep disruption Sleep & Energy Insomnia Difficulty staying asleep Non-restorative sleep Low motivation Daytime tiredness Hormonal & Neuroendocrine Symptoms PMS PMDD Low libido Stress-related hormone imbalance Key Features 42 total biomarkers Advanced LCMS laboratory analysis Diurnal cortisol & melatonin assessment Neurotransmitter pathway analysis At-home dried urine collection Non-invasive testing Suitable for adults and children Specialist PhD interpretation included Clinical literature-cited report UK delivery included Laboratory fee included Results available within 3–5 working days after laboratory receives samples Why Assess Cortisol & Neurotransmitters Together? Stress hormones and neurotransmitters constantly interact. Chronic stress may alter: Cortisol rhythm Dopamine function Serotonin balance Sleep quality Energy production Emotional regulation By testing neurotransmitters alongside cortisol and melatonin, this profile provides a more complete overview of neuroendocrine health and stress physiology. Benefits of This Advanced Profile Comprehensive Neuroendocrine Assessment Provides insight into both neurotransmitter and stress hormone balance. Objective Functional Data Offers measurable biomarker information to complement clinical assessments. Personalised Health Insights Helps healthcare practitioners identify potential imbalances and guide targeted interventions. Stress & Sleep Evaluation Assesses cortisol rhythm and melatonin metabolism associated with: Sleep quality Burnout Fatigue Stress resilience Mood & Cognitive Support Supports investigation of symptoms related to: Anxiety Depression Focus Mood Cognitive function How Sample Collection Works The test uses convenient dried urine collection. Four urine samples are collected throughout the day: Morning Mid-morning Early evening Bedtime Samples are collected onto filter strips and dried before being returned to the laboratory. This non-invasive collection method is simple, practical, and suitable for home use. What’s Included in the Kit? Your kit includes: Test requisition form Symptom checklist Collection instructions Dried urine collection cards Return envelope Shipping guidance Results & Specialist Interpretation Results are typically available within: 3–5 working days after the laboratory receives your samples. Your confidential report includes: Easy-to-read graphics Biomarker values Specialist PhD interpretation Clinical comments Functional health insights Suitable For This test may be beneficial for individuals experiencing: Anxiety Depression Chronic stress Burnout Poor sleep Brain fog Mood instability ADHD-related symptoms Low energy Fatigue Cognitive difficulties Stress-related hormone imbalance Frequently Asked Questions Is this test suitable for home use? Yes. The test is designed for easy at-home sample collection. Is the test invasive? No. This is a non-invasive dried urine test. Is the laboratory fee included? Yes. No additional laboratory fee or tax is required. How quickly will I receive my results? Results are generally available within 3–5 working days after the laboratory receives your samples. Is this test suitable for children? Yes. The test is suitable for both adults and children. What technology is used? Advanced LCMS (Liquid Chromatography–Mass Spectrometry) analysis. Test Info Test ID: U-342 | LCMS Neurotransmitters and Diurnal Hormones I Trp, 5-HT, 5-HIAA, GABA, Gly, Tau, Glu, Gln, His, HIST, N-MeHist, PEA, Tyr, Tyra, DA, DOPAC, HVA, NE, NMN, Epi, VMA, Kyn, KynAc, 3OHKyn, Xanth, Crtn(x5), FC(x4), FCn(x4), MT6s(x4) Sample Type: Dried Urine Technology: Advanced LCMS (Liquid Chromatography–Mass Spectrometry) analysis with specialist laboratory interpretation included in your personalised laboratory report.
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