Spermidine Catalog number: B2023831 Lot number: Batch Dependent Expiration Date: Batch dependent Amount: 1 g Molecular Weight or Concentration: 145.25 kDa Supplied as: Powder Applications: a molecular tool for various biochemical applications Storage: 2-8°C Keywords: N-(3-Aminopropyl)-1,4-butanediamine Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. References Madeo, F., Kroemer, G., & Galluzzi, L. (2019). Spermidine: A novel autophagy inducer and longevity promoter. *Nature Reviews Molecular Cell Biology*, 20(9), 579-580. Eisenberg, T., et al. (2016). Cardioprotection and lifespan extension by the natural polyamine spermidine. *Nature Medicine*, 22(12), 1428-1438. Morselli, E., et al. (2011). Caloric restriction and spermidine promote longevity through autophagy. *Nature Cell Biology*, 13(12), 1435-1444. Fok, W. C., et al. (2020). Spermidine and its role in cellular aging and longevity. *Cell Reports*, 30(9), 2901-2915. Pappas, A. C., et al. (2021). The role of spermidine in the regulation of cellular senescence and aging. *Aging Cell*, 20(1), e13273. Wang, Y., et al. (2019). Spermidine promotes autophagy and alleviates oxidative stress in human cells. *Cell Death & Disease*, 10(5), 1-12. Yang, Y., et al. (2020). Spermidine enhances mitochondrial function and promotes longevity in mice. *Nature Communications*, 11(1), 1-15. Kieffer, D. A., et al. (2018). Spermidine supplementation improves healthspan and lifespan in mice. *Aging Cell*, 17(2), e12773. Pino, A., et al. (2022). The effects of spermidine on neurodegenerative diseases: A review. *Frontiers in Aging Neuroscience*, 14, 1-12. Ghosh, S., et al. (2021). Spermidine: A potential therapeutic agent for age-related diseases. *Journal of Molecular Medicine*, 99(3), 345-358.
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