THC necklace | sterling silver The brain has a built-in system that responds to cannabis. We know this only because people kept getting high enough to notice and chemists eventually asked why the molecule worked. The full answer took decades and revealed receptor families that no one was looking for. The Science Behind THC Delta-9-tetrahydrocannabinol was isolated and structurally characterised by Raphael Mechoulam and Yechiel Gaoni in 1964. The CB1 receptor was identified by Lisa Matsuda's group in 1990, and the brain's endogenous cannabinoid anandamide was discovered in 1992 by William Devane and Mechoulam. Together with 2-arachidonoylglycerol, identified in 1995, the endocannabinoid system is now known to regulate synaptic plasticity, mood, pain modulation, appetite, sleep, and immune function. Therapeutic applications include cannabinoid-based treatments for chemotherapy-induced nausea (the synthetic THC analog dronabinol) and pain associated with multiple sclerosis. Worn By Cannabinoid pharmacology has become a respectable research field over the past decade. neuropharmacologists and cannabinoid researchers pain medicine clinicians and palliative care physicians medicinal chemists working on receptor-targeted compounds patients in cannabinoid clinical trials or compassionate-use programmes Most often given to a colleague who runs cannabinoid trials, or to a researcher whose lab handled THC before that was easy to do. Explore Related Molecules Jewelry THC necklace | gold vermeil THC necklace 3D | silver Psilocybin necklace | silver Fluoxetine necklace | silver Propofol necklace | silver FAQ Who tends to buy the silver THC necklace versus the gold? Buyer pattern splits along material. The silver tends to go to working researchers and clinicians who wear it as daily-bench attire. The gold tends to go as a milestone or graduation gift. Same molecule, different occasion. Why is THC such a foundational molecule in modern neuroscience? Because mapping how a single plant alkaloid produces its cognitive effects revealed that the brain runs a parallel signalling system on its own internal cannabinoids. The endocannabinoid system was found because researchers asked what THC was binding to. Discovery direction matters. What are the size, material, and chain specs? 45 mm pendant in 925 polished sterling silver, nickel-free. 45 cm sterling silver chain with a 5 cm extender. Free worldwide DHL Express, 1-5 business days, duties and taxes covered. 30-day “Love It or Return It” policy. How does the silver compare to the gold THC necklace? Same molecule, same 45 mm size. The silver here is solid 925 sterling. The gold version is sterling silver core with 2.5 micron 18K gold plating. The catalog also includes a separate 3D THC silver necklace, listed as THC necklace 3D, with the same 45 mm pendant size.
