ThiActive B complex contains a full spectrum of B vitamins in their active forms, including methylated folate and vitamin B12. Also included are two highly bioavailable vitamin B1 derivatives, thiamine tetrahydrofurfuryl disulfide (TTFD) and benfotiamine. How to use Start with one capsule per day in the morning with or without food. This can be increased to 2 capsules per day to reach a maximum dose. Avoid coffee/tea consumption either one hour before or two hours after. Avoid taking this product in the afternoon/evening, as it may interfere with sleep. For those who consider themselves sensitive to methylated B vitamins, consider using our non-methylated B complex Thiavite. Important information: In some individuals, supplementation with products containing thiamine tetrahydrofurfuryl disulfide (TTFD) can induce a temporary worsening of certain symptoms such as fatigue, brain-fog, and digestive bloating or gas. This usually lasts for around one week, and is referred to as the “paradoxical reaction”. For those with sensitivity to sulfur-containing compounds, this product may not be suitable.