L-5-Methyltetrahydrofolate Active Vitamin B9 Folate Supplement For mood, heart health & fetal development Nerve support* 5-MTHF, L-5-Methyltetrahydrofolate, also known as Methylfolate, is the preferred form of folate supplementation because it is the active form of folate used by the body’s tissues.* Many individuals don't get sufficient 5-MTHF (L-5-Methyltetrahydrofolate), the active form of folic acid, because they have intestinal or liver dysfunction, or because they are among the three out of five Americans whose genetic makeup makes it difficult to convert folic acid into active 5-MTHF. Features 5-MTHF is an active, tissue-ready form of folate, an essential B vitamin that supports heart, brain, and blood health.* Healthy Methylation: A breakthrough in active folate supplementation for healthy methylation Positivity Support: 5-MTHF contributes to the production of serotonin, melatonin, dopamine, all of which support positivity Nerves & Circulation: Supports healthy blood vessel and nerve function Free From: Doesn't contain gluten, eggs, tree nuts, peanuts, dairy, yeast, soy, fish, or shellfish NPN 80020108 Benefits of Thorne’s 5-MTHF: An adequate amount of 5-MTHF is essential for the production of the neurotransmitters serotonin, melatonin, dopamine, and epinephrine – all of which support healthy brain function and mood* Acting with vitamin B12, 5-MTHF functions as a methyl-group donor, thereby facilitating healthy methylation and homocysteine levels* Folic acid is especially important before conception and during early pregnancy, because its biggest need is during the first trimester – when a woman might not know she is pregnant. A folic acid deficiency is linked to low-birth-weight infants and neural tube birth defects* Note: 1 mg of 5-MTHF is recommended for fetal support during pregnancy; the 15 mg option is recommended only when directed by a health-care practitioner. The body's conversion of synthetic, inactive folic acid is a multi-step biochemical process that occurs in the intestines and liver. In the presence of intestinal or liver dysfunction this conversion may not be sufficient to meet the body's needs. Furthermore, up to 60 percent of the Canadian population may have a genetic enzyme defect that makes it difficult for them to convert folic acid into active 5-MTHF. For these individuals and many others, 5-MTHF supplementation may be a more effective method of folate repletion. In concert with vitamin B12, 5-MTHF functions as a methyl-group donor involved in the conversion of the amino acid homocysteine to methionine. Methyl-group donation is vital to many biochemical processes, including the synthesis of serotonin, melatonin, and DNA. 5-MTHF is also involved in production of the catecholamine neurotransmitters (dopamine, norepinephrine, epinephrine) and the production of beneficial nitric oxide in vascular endothelial cells, which promotes healthy blood vessel function. Ingredient Information Key Ingredients 5-MTHF Serving Size: 1 Capsules Servings Per Container: 60 Name Amount Folate (L-5-MTHF) 1.7mg DFE Other Ingredients: Hypromellose Capsule, Leucine, Microcrystalline Cellulose, Silicon Dioxide How to Use Take 1 capsule one to three times daily or as recommended by your health professional. ALLERGY WARNING This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.PREGNANCY WARNING If pregnant, consult your health professional before using this product.INTERACTIONS 5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate. Legal Disclaimer * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. The product information on this website may not be 100% accurate. Please ensure to check the product packaging information before consumption, especially if you have allergies or other health conditions.
