Thorne Methyl-Guard Thorne Methyl-Guard is a comprehensive methylation support formula designed to promote cardiovascular, cognitive, bone, and nervous system health.* This advanced supplement provides key methyl donors and cofactors that support the body’s essential methylation processes.* Formulated by Thorne, Methyl-Guard combines betaine (trimethylglycine) with the active, tissue-ready forms of folate (5-MTHF), vitamin B12 (methylcobalamin), and vitamin B6 (pyridoxal-5′-phosphate, P5P).* These nutrients work together to support healthy methylation and help maintain normal homocysteine levels in the blood—an important factor in cardiovascular health.* Methylation is involved in numerous biochemical processes throughout the body, including neurotransmitter balance, detoxification pathways, redox balance, and cellular repair.* By supporting healthy methylation, Methyl-Guard helps maintain heart and blood vessel health, cognitive and nerve function, bone integrity, eye health, muscle function, and female reproductive health.* Key Benefits: Supports healthy methylation processes* Helps maintain normal homocysteine levels* Supports cardiovascular and blood vessel health* Promotes cognitive, nerve, and mood support* Supports bone and muscle health* Provides active forms of B vitamins for optimal absorption*