Thorne PharmaGABA – Natural GABA Support for Sleep, Stress & Focus Thorne PharmaGABA features a natural form of gamma-aminobutyric acid (GABA)—the brain’s primary inhibitory neurotransmitter—designed to support restful sleep, stress regulation, and a calm yet focused state of mind*. GABA functions like a neurological “brake,” helping quiet excessive brain activity and promote relaxation without sedation.* Clinical research shows that the natural PharmaGABA used in Thorne’s formula can help reduce stress-related beta brain waves while increasing alpha waves, which are associated with relaxed alertness.* This shift supports physical calm while maintaining mental clarity—making PharmaGABA useful during periods of stress, before sleep, or when focus under pressure is needed.* Additional studies demonstrate physiological signs of relaxation with natural PharmaGABA, including reduced pupil diameter, heart rate, and key stress biomarkers such as salivary cortisol and chromogranin A*. These findings support PharmaGABA’s role in promoting the body’s natural relaxation response.* Importantly, in a head-to-head, double-blind clinical trial, synthetic GABA did not demonstrate the same supportive effects as natural PharmaGABA.* This highlights the importance of GABA’s natural fermentation-derived form. Thorne offers two strengths to meet individual needs: PharmaGABA-100 – 100 mg of natural GABA per capsule PharmaGABA-250 – 250 mg of natural GABA per capsule Both formulas are non-habit forming and suitable for daily use. Key Benefits Supports restful sleep* Helps the brain manage stress and tension* Promotes calm focus and mental clarity* Encourages relaxed alertness by supporting healthy brain wave balance* Helps reduce physical markers of stress* Non-habit forming natural GABA Available in 100 mg and 250 mg strengths Ideal For Sleep support* Stress management* Sports performance and recovery* Individuals seeking calm focus without sedation* Manufactured by Thorne, a trusted leader in research-driven, clinical-grade supplementation. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
