Thorne Advanced Bone Support (Formerly Oscap) supports bone health by providing B vitamins for healthy methylation and boron. Women over the age of 65 should take a supplement to support bone health. Adequate magnesium intake promotes bone density by optimizing the secretion of parathyroid hormone and facilitating active calcium transport to the bones. Advanced Bone Support provides vitamin D3, which facilitates the absorption of calcium; boron, which assists the body's metabolism of vitamin D and estrogen; and B vitamins for healthy methylation, which mediates homocysteine levels, a known risk factor of low bone density. Groups at particular risk for bone loss in addition to women include smokers, those with a sedentary lifestyle, individuals who consume excessive sugar, alcohol, or caffeine, small-boned individuals. Recommended use: Take 2 capsules, 2 times daily or as directed by a healthcare professional. Thorne Advanced Bone Support Facts: 2 capsules contain: Vitamin D (as Vitamin D3) (1,000 IU) 25 mcg Vitamin B6 (as Pyridoxal 5'-Phosphate) 20 mg Folate (100mcg as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt) 166.6 mcg DFE Vitamin B12 (as Methylcobalamin) 50 mcg Calcium (as DimaCal DiCalcium Malate) 300 mg Magnesium (as Albion DiMagnesium Malate) 100 mg Boron (as Bororganic Boron Glycinate Complex) 3 mg Other Ingredients: Hypromellose (derived from cellulose) capsule, Medium Chain Tryglyceride Oil.