tiliGRID: Ultra-Precise Single-Molecule Placement in Seconds tiliGRID is a ready-to-use microscopy slide on an anti-fouling surface that enables nanoscale control over where your molecules bind, minimizing background and turning single-molecule experiments into a fast, robust routine. Four-dot biotin handles are arranged on a DNA Origami imprinted surface, providing well-defined, repeatable attachment sites for your biotinylated targets and eliminating random binding. With its simple placement workflow—just pipette and play—tiliGRID streamlines sample prep into a straightforward, few-minute procedure with no purification, titration, or concentration adjustments needed. This precisely engineered nanoarchitecture gives you precise molecule placement and high signal clarity, empowering confident localization, and quantitative single‑molecule readouts.
