Identify targets in electron microscopy, cryo-EM and cryo-ET with a label that also carries a fluorescent signal. tiliPOINTER combines AF647 dyes, anti-rabbit binding and one or three gold nanoparticles on a DNA nanostructure. Fluorescence helps locate a target or region of interest; gold provides electron contrast. The three-particle row points towards the binding end, adding a recognizable geometry for connecting the label with its molecular surroundings. Choose your format tiliPOINTER-1: one 10 nm gold nanoparticle. tiliPOINTER-3: a row of three 10 nm gold nanoparticles. Stabilization: standard or ruggedized. Supplied amount 10 pmol in 200 µL at 50 nM. Develop labeling for isolated complexes, accessible cell-surface targets or exposed targets in sections. For other particle arrangements, dyes or binders, request a custom tiliPOINTER. For research use only. Not for diagnostic use.
